Dispenser having a cartridge holder

A system having:

• a) a dispenser including a cartridge holder;
• b) a cartridge receptacle including:
• i) a mixing chamber in which a diluent and a beverage substrate are mixed;
• ii) an inflow for the diluent, wherein the inflow is provided in a wall or a bottom of the mixing chamber;
• iii) an outflow, wherein the outflow is provided in the wall or the bottom of the mixing chamber;
• and
• iv) a piercing means for perforating a membrane, wherein the piercing means is provided within the mixing chamber, and wherein the piercing means is located within a direction of flow between the inflow and the outflow;
• c) a cartridge with a cavity in which the beverage substrate is located, which is closed by means of the membrane;
• wherein the cartridge holder has at least one guide, at least one twist prevention means, or both the at least one guide and the at least one twist prevention means for the cartridge, the cartridge receptacle, or both the cartridge and the cartridge receptacle;
• and
• wherein the cartridge holder has a cutout which at least partially receives the cartridge, at least partially receives the cartridge receptacle, or at least partially receives both the cartridge and the cartridge receptacle.