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US 11,478,499 B2Granted
Compositions for use to treat cataract
AssigneesUniversiteit Gent, Vib Vzw
InventorsElisabeth Van Aken, Joris Delanghe, Nico Callewaert, Loes Van Schie
Life of this patent
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Abstract
A non-surgical treatment of cataract in a human or animal. The invention specifically relates to the administration of a deglycating enzyme and its cofactor(s), which results in the deglycation of the lens crystallins. The disclosure thus relates to a minimal invasive type of treatment of cataract, which is easier and cheaper compared to existing surgical methods.
Claims19
A composition comprising:
- a fructosamine-3-kinase, and
- adenosine triphosphate (ATP) and/or an ATP regenerating system,
- in amounts useful to treat a cataract in a human or an animal subject,
- wherein the composition is configured for intravitreal injection into the subject.
1 more element
A method of treating a human or animal subject having a cataract, the method comprising:
- administering to the subject a composition comprising a fructosamine-3-kinase and adenosine tri phosphate (ATP)
- so as to treat the subject's cataract.
A method for treating a human or animal subject having a cataract, the method comprising:
- administering to the subject a composition comprising a fructosamine-3-kinase and an adenosine triphosphate regenerating system so as to treat the cataract.
Dependencies are inferred from the claim text.