Cellular targeted active ingredient delivery system
AssigneeCellis AG
InventorsMagdalena Krol, Irene Benni, Paola Baiocco, Tomasz Rygiel, Alberto Boffi
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Abstract
The present invention relates to an isolated cellular targeted delivery system comprising a CD45+ leukocyte cell comprising within said cell a complex of one or more iron binding proteins and an active ingredient as well as methods for producing such isolated cellular targeted delivery system and uses of such system for therapy, in particular for therapy of cancer.
Claims9
An isolated targeted delivery system comprising a macrophage comprising within said macrophage a complex of ferritin and an anti-cancer drug, wherein the anti-cancer drug is encapsulated within a ferritin multimer, and wherein there is no covalent or non-covalent bond between the ferritin and the anti-cancer drug.
Dependencies are inferred from the claim text.