Endotoxin detection device and endotoxin detection method

A method for producing a medical solution by using a medical solution production system comprising an endotoxin detection device incorporated into an artificial dialysate line, wherein

• the endotoxin detection device does not use Limulus Amebocyte Lysate reagent and comprises:
• a region containing the electrolyte solution in the artificial dialysate line;
• a partitioning member that partitions the region into two compartments such that the two compartments are in communication via a nanopore;
• a first electrode that is disposed in a first compartment;
• a second electrode that is disposed in a second compartment and is electrically connected to the first electrode;
• an electrolyte solution flow generating device configured to cause the electrolyte solution in the first compartment to move to the second compartment via the nanopore;
• an application device configured to apply voltage between the first electrode and the second electrode;
• and
• a monitoring device configured to monitor ion current flowing in the nanopore,
• the electrolyte solution is an artificial dialysate flowing in the artificial dialysate line, and
• using the endotoxin detection device to detect an endotoxin in the flowing electrolyte solution.