Method of using hydrophilized bactericidal polymers
AssigneePurdue Research Foundation
InventorsJeffrey P. Youngblood, Philippe H. Sellenet
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Abstract
A bactericidal polymeric composition includes a hydrophilic first comonomer copolymerized to a second comonomer to produce a polymeric composition that is more hydrophilic or more bactericidal in an aqueous solution than either of the comonomers alone. Methods for identifying bactericidal polymers, methods for rendering materials bactericidal, and methods for using bactericidal compositions to kill or reduce bacterial growth are also described. Applications for the inventive compositions include their use in catheters, stents, medical devices, contact lenses; root canal fillers; and/or wound dressings.
Claims13
A method of reducing a number of bacteria comprising
- a. contacting the bacteria and a bactericidal copolymer, and
- b. reducing growth of the bacteria with the bactericidal copolymer,
- c. wherein the bactericidal copolymer is a copolymer comprising
- i. a 4-vinyl pyridine, wherein the 4 vinyl pyridine is quaternized with an alkyl group;
- and
- ii. a hydrophilic comonomer comprising a PEG ester having an acrylate or a methacrylate group.
Dependencies are inferred from the claim text.