Sorbent for a dialysis device and dialysis system
AssigneesTemasek Polytechnic, Awak Technologies Pte Ltd
InventorsChristian Gert Bluchel, Peter Haywood
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Abstract
The invention relates to a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a soluble source of sodium ions. The sorbent comprises an ion exchange system which converts urea to ammonium ions and which is configured to exchange ammonium ions for predominantly hydrogen ions and to exchange Ca, Mg, and K for predominantly sodium ions. The soluble source of sodium ions overcomes an initial drop in sodium concentration in regenerated dialysate. When used in conjunction with an infusion system configured to utilise exchange of Ca, Mg and K for sodium during dialysate regeneration a desired sodium ion concentration can be maintained.
Claims8
A sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a homogeneous mixture of:
- (a) uremic toxin-treating enzyme particles comprising a uremic toxin-treating enzyme immobilized on a solid support;
- (b) cation exchange particles configured to exchange ammonium ions for hydrogen ions and to exchange calcium, magnesium, and/or potassium cations for sodium ions such that at least 80% of exchanged ammonium ions are exchanged for hydrogen ions, and at least 80% of exchanged calcium, magnesium, and/or potassium cations are exchanged for sodium ions;
- and
- (c) anion exchange particles, and further comprising a soluble source of sodium ions, wherein the cation exchange particles are set to a pH range of from 3.5 to 5.0.
Dependencies are inferred from the claim text.