Back to results
US 11,456,071 B2Granted
Hemostatic parameter display
AssigneeHemoSonics LLC
InventorsFrancesco Viola, William F. Walker, Gregory V. Browne, Adam Looker, Bryan Roy, Bjarne Hansen
Life of this patent
Estimating the term…
Abstract
A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.
Claims21
A system for measuring physiologic parameters of a single blood sample, the system comprising:
- a receptacle to receive a cartridge, the cartridge having:
- a plurality of sample wells including a first sample well and a second sample well;
- and
- a plurality of channels including i) a first channel connected in fluid communication to the first sample well and ii) a second channel connected in fluid communication to the second sample well;
- wherein the plurality of channels have a collective connection configured to establish fluid communication with the single blood sample for drawing, from the single blood sample, portions for each of the first and second the sample wells including a first portion for the first sample well and a second portion for the second sample well, respectively;
- a sensor system configured to couple with the receptacle for interrogation of the plurality of portions of the single blood sample including the first and second portions of the single blood sample to yield a plurality of sets of independent measurements including a first set of independent viscoelastic measurements from the first portion and a second set of independent viscoelastic measurements from the second portion;
- a processor connected to the sensor system to continually receive the plurality of sets of independent measurements, including a data sets associated with the first set of independent viscoelastic measurements and a data sets associated with the second set of independent viscoelastic measurements, the processor being configured, via a set of instructions stored in memory, to estimate physiologic parameters of the single blood sample;
- and
- a graphical user interface (GUI) connected to the processor and configured to simultaneously display functional hemostatic index derived from each of the plurality of independent measurements, wherein each displayed functional hemostatic index of the simultaneously displayed functional hemostatic indexes comprise a coagulation factor function, a fibrinogen function, and the platelet function, wherein the graphical user interface comprises a graphical indicator for each of the displayed hemostatic indexes.
6 more elements
A method for measuring physiologic parameters of a single blood sample, the method comprising:
- interrogating a cartridge to provide a plurality of sets of independent measurements including a first set of independent viscoelastic measurements from the first portion and a second set of independent viscoelastic measurements from the second portion;
- wherein the cartridge has (i) a plurality of sample wells including a first sample well and a second sample well and (ii) a plurality of channels including a) a first channel connected in fluid communication to the first sample well and b) a second channel connected in fluid communication to the second sample well, wherein the plurality of channels have a collective connection configured to establish fluid communication with the single blood sample for drawing, from the single blood sample, portions for each of the first and second the sample wells including a first portion for the first sample well and a second portion for the second sample well, respectively;
- continually receiving, by a processor, the plurality of sets of independent measurements, including a data sets associated with the first set of independent viscoelastic measurements and a data sets associated with the second set of independent viscoelastic measurements;
- estimating, by the processor, a functional hemostatic index associated with the platelet function by differentially combining results derived from at least the first and second independent measurements;
- and
- simultaneously displaying, via a graphical user interface, functional hemostatic indexes derived from each of the plurality of independent measurements, wherein each displayed functional hemostatic index of the simultaneously displayed functional hemostatic indexes comprise a coagulation factor function, a fibrinogen function, and the platelet function, and wherein the graphical user interface comprises a graphical indicator for each of the displayed hemostatic indexes.
3 more elements
Dependencies are inferred from the claim text.