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A system for analysing sets of medical images, the system comprising:

• a user terminal operable to input diagnosis metadata for at least a first set of images and a second set of images;
• and
• a processing unit configured to
• independently analyse at least the first set of images and the second set of images to determine a malignancy output across at least the first set of images and the second set of images,
• generate output data based on the determined malignancy output at least by determining a first average malignancy output of the first set of images, determining a second average malignancy output of the second set of images, and determining the greater of the first average malignancy output and the second average malignancy output, and
• determine a degree of similarity between the malignancy output and the diagnosis metadata, wherein, if the degree of similarity is below a predetermined threshold, produce an output to trigger a further analysis of at least the first set of images and the second set of images.

A non-transitory computer readable medium comprising instructions which, when executed by a computer, cause the computer to carry out a process for analysing medical images, the process comprising:

• receiving a plurality of medical images, comprising a first set of images and a second set of images;
• using one or more trained machine learning models to independently analyse the medical images to determine a malignancy output across the plurality of medical images;
• generating output data based on the determined malignancy output, wherein generating the output data comprises
• determining a first average malignancy output of the first set of images,
• determining a second average malignancy output of the second set of images, and
• determining the greater of the first average malignancy output and the second average malignancy output;
• receiving input data relating to manually determined characteristics of the one or more medical images;
• determining a degree of similarity between the malignancy output and the manually determined characteristics;
• and
• in response to the degree of similarity being below a predetermined threshold, producing an output to trigger a further analysis of the medical images.