Providing an optimum subtraction data set

A medical imaging device comprising:

• a processor configured to:
• receive first image data sets that map an object under examination within a first time phase, wherein the first image data sets are acquired by the medical imaging device;
• receive at least one second image data set that maps the object under examination within a second time phase, wherein the at least one second image data set is acquired by the medical imaging device or another medical imaging device, and wherein the at least one second image data set maps a change in the object under examination with respect to the first time phase;
• divide the at least one second image data set into a plurality of spatial image regions;
• generate subtraction image regions for the plurality of spatial image regions by subtracting corresponding image regions of the first image data sets from each image region of the plurality of spatial image regions of the at least one second image data set;
• determine an image quality parameter for each subtraction image region of the subtraction image regions;
• determine an optimum subtraction image region for each image region of the plurality of spatial image regions of the at least one second image data set by a comparison of the image quality parameters;
• generate an optimum subtraction data set from the optimum subtraction image regions;
• and
• provide the optimum subtraction data set.

A non-transitory computer program product comprising a program configured to be directly loaded into a memory of a programmable processor of a medical imaging device, wherein the program, when executed in the processor, is configured to cause the medical imaging device to:

• receive first image data sets that map an object under examination within a first time phase, wherein the first image data sets are acquired by the medical imaging device;
• receive at least one second image data set that maps the object under examination within a second time phase, wherein the at least one second image data set is acquired by a same or another medical imaging device, and wherein the at least one second image data set maps a change in the object under examination with respect to the first time phase;
• divide the at least one second image data set into a plurality of spatial image regions;
• generate subtraction image regions for the plurality of spatial image regions by subtracting corresponding image regions of the first image data sets from each image region of the plurality of spatial image regions of the at least one second image data set;
• determine an image quality parameter for each subtraction image region of the subtraction image regions;
• determine an optimum subtraction image region for each image region of the plurality of spatial image regions of the at least one second image data set by a comparison of the image quality parameters;
• generate an optimum subtraction data set from the optimum subtraction image regions;
• and
• provide the optimum subtraction data set.