Sample probe for dissolution testing and the like
AssigneeDistek, Inc.
InventorsJeffrey Brinker, Shawn Craig, Peter K. Schultz, Timothy John Nadolski
Life of this patent
Estimating the term…
Abstract
In one embodiment, a sample probe has a cap and a base, wherein the cap includes a grip portion and a projection portion. The projection portion fits within a hollow portion of a filter such that the filter is disposed on the outside of the projection portion and the filter and the cap form a cap assemblage. The base comprises a base recess that receives a portion of the cap assemblage including the filter. The cap and base include corresponding media transfer regions adjacent and connected to the filter that reduces flow resistance and chances of blockage and/or contamination during dissolution-testing sampling using the sample probe.
Claims21
An article of manufacture comprising:
- a cap having a projection with a duct through the projection;
- and
- a base having a recess and a duct in fluid communication with the recess of the base, wherein:
- the projection is adapted to fit within a recess of a filter to form a cap-filter assemblage;
- the filter and the projection of the cap-filter assemblage are adapted to fit within the recess of the base to form a cap-filter-base assemblage;
- the cap-filter-base assemblage defines at least one media transfer region adjacent to the filter;
- and
- the duct of the base in the cap-filter-base assemblage is adapted to receive a cannula to form a sample probe;
- a first cone-shaped media transfer region is defined by an inner surface of the filter and a cone-like depression in the cap's projection that is in fluid communication with the cap's duct such that the larger end of the first cone-shaped media transfer region faces a bottom of the filter;
- a second cone-shaped media transfer region is defined by an outer surface of the filter and a cone-like depression in the base that is in fluid communication with the base's duct such that the larger end of the second cone-shaped media transfer region faces the bottom of the filter;
- the distal end of the cap comprises a substantially annular recess defined by the cap's projection and an outer wall of the cap;
- the cap's projection is disposed within the cap's recess;
- the cap's recess is adapted to receive the filter, such that the filter is within the cap's recess when the cap-filter assemblage is formed;
- the cap's recess is adapted to receive a portion of the base when the cap-filter-base assemblage is formed;
- and
- the cap's recess has a first supplementary recess at the distal end of the cap, which provides additional room for manually gripping the filter.
An article of manufacture comprising:
- a cap having a projection with a duct through the projection;
- and
- a base having a recess and a duct in fluid communication with the recess of the base, wherein:
- the projection is adapted to fit within a recess of a filter to form a cap-filter assemblage;
- the filter and the projection of the cap-filter assemblage are adapted to fit within the recess of the base to form a cap-filter-base assemblage;
- the cap-filter-base assemblage defines at least one media transfer region adjacent to the filter;
- the duct of the base in the cap-filter-base assemblage is adapted to receive a cannula to form a sample probe;
- a first cone-shaped media transfer region is defined by an inner surface of the filter and a cone-like depression in the cap's projection that is in fluid communication with the cap's duct such that the larger end of the first cone-shaped media transfer region faces a bottom of the filter;
- a second cone-shaped media transfer region is defined by an outer surface of the filter and a cone-like depression in the base that is in fluid communication with the base's duct such that the larger end of the second cone-shaped media transfer region faces the bottom of the filter;
- the cap comprises a top portion and a bottom portion;
- the bottom portion comprises a rigid plastic;
- and
- the top portion comprises a more elastic material than the rigid plastic, for providing better grip support.
Dependencies are inferred from the claim text.