Method for the in vitro diagnosis or prognosis of ovarian cancer
AssigneeBiomerieux
InventorsPhilippe Perot, François Mallet, Nathalie Mugnier
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Abstract
The present invention relates to a method for the in vitro diagnosis or prognosis of ovarian cancer, which includes a step of detecting at least one expression product of at least one HERV nucleic acid sequence, the use of said nucleic acid sequences, once isolated, as one or more molecular marker(s) and a kit including at least one specific binding partner of at least one of the expression products of the HERV nucleic acid sequences.
Claims19
A method for detecting at least two RNA transcripts, comprising:
- obtaining a biological sample that is collected from a human patient suspected of having ovarian cancer;
- and
- detecting, in the biological sample, the presence or absence of at least two RNA transcripts comprising a first RNA transcript expressed by a first nucleic acid sequence having at least 99% identity with SEQ ID NO:
- 2, and a second RNA transcript expressed by a second nucleic acid sequence having at least 99% identity with SEQ ID NO:
- 3.
A method for detecting at least two RNA transcripts comprising:
- obtaining a biological sample that is collected from a human patient that has been diagnosed with ovarian cancer;
- and
- detecting, in the biological sample, the presence or absence of at least two RNA transcripts comprising a first RNA transcript expressed by a first nucleic acid sequence having at least 99% identity with SEQ ID NO:
- 2, and a second RNA transcript expressed by a second nucleic acid sequence having at least 99% identity with SEQ ID NO:
- 3.
A method for detecting at least two RNA transcripts, comprising:
- obtaining a biological sample that is collected from a human patient suspected of having ovarian cancer;
- detecting, in the biological sample, the presence or absence of a first RNA transcript expressed by a first nucleic acid sequence having at least 99% identity with SEQ ID NO:
- 2 by contacting the first RNA transcript or cDNA obtained therefrom with a first probe or primers to respectively hybridize to or amplify a region within the first RNA transcript or cDNA obtained therefrom that is defined by a distinct region within the first nucleic acid sequence;
- and
- detecting, in the biological sample, the presence or absence of a second RNA transcript expressed by a second nucleic acid sequence having at least 99% identity with SEQ ID NO:
- 3 by contacting the second RNA transcript or cDNA obtained therefrom with a second probe or primers to respectively hybridize to or amplify a region within the second RNA transcript or cDNA obtained therefrom that is defined by a distinct region within the second nucleic acid sequence.
Dependencies are inferred from the claim text.