Analysis of Y-chromosome STR markers
OwnerRixun Fang, Manohar Furtado +2inventors
InventorsRixun Fang, Manohar Furtado, Manfred Kayser, Kaye Ballantyne
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Abstract
The methods and compositions provided herein relate to the discovery of 13 STR markers, found on the human Y chromosome, having surprisingly high mutation rates when compared with 173 other Y-STR markers known today. The set of RM-Y-STRs may overcome the current dilemma of Y-chromosome analysis in forensic applications due to their extraordinary mutation properties. Embodiments of the invention include methods for allelic determination of rapidly-mutating Y-STR markers, amplification primers for the analysis of rapidly-mutating Y-STR markers, allelic ladders for analysis of rapidly-mutating Y-STR markers, and kits for the analysis of rapidly-mutating Y-STR markers.
Claims17
A method of determining a selection of Y-STR markers for a male individual, the method comprising determining the allele of at least seven Y-STR markers selected from the group consisting of DYF387S1, DYF399S1, DYF403S1, DYF404S1, DYS449, DYS518, DYS526, DYS547, DYS570, DYS576, DYS612, DYS626 and DYS627.
A method of determining a selection of Y-STR markers for a male individual, the method comprising determining the allele of at least six Y-STR markers selected from the group consisting of DYF387S1, DYF399S1, DYF404S1, DYS449, DYS526, DYS547, DYS570, DYS576, DYS612, DYS626 and DYS627.
Dependencies are inferred from the claim text.