Crispr-CAS10 systems and methods for phage genome editing

A phage genome editing system comprising:

• a Staphylococcus bacterial cell that can be infected by a phage;
• a vector comprising a crRNA that can hybridize to a nucleic acid sequence of the phage;
• and
• a vector comprising a donor nucleic acid sequence, wherein the donor nucleic acid sequence comprises:
• a mutated nucleic acid sequence to be introduced into the phage, flanked by two nucleic acid sequences containing regions of homology to the phage genome.