Pancreatic islet-like cell structures and a method of preparing thereof
AssigneeFresenius Medical Care Deutschland GmbH
InventorsCiro Tetta, Giovanni Camussi, Sara Giunti, Victor Manuel Navarro Tableros
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Abstract
The invention relates to a method of preparing pancreatic islet-like cell structures characterized by a unique combination of morphological and functional features which make them particularly suitable for use in both clinical and drug screening application, as well as to the pancreatic islet-like cell structures obtained therefrom.
Claims3
An artificially grown spheroid pancreatic islet-like cell structure having a diameter of from 50 to 250 μm and comprising differentiated cells derived from a human liver stem cell (HLSC) and expressing the pancreatic hormones insulin, glucagon, pancreatic polypeptide, somatostatin, and ghrelin and the markers PDX-1 and NgN3.
Dependencies are inferred from the claim text.