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US 11,453,684 B2Granted
Method of treating a proliferative disorder by administering a thiourea gold(I) complex
AssigneeKing Fahd University of Petroleum and Minerals
InventorsAnvarhusein A. Isab, Adam A. A. Sulaiman
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Abstract
The invention is directed to a method of treatment of proliferative diseases or disorders such as cancer with gold(I) N-heterocyclic carbene (NHC) thiourea or substituted thiourea complexes, to the complexes per se and to therapeutic compositions containing these gold(I) based complexes.
Claims12
A therapeutic method for treating a proliferative disease or disorder in a subject in need thereof, comprising:
- administering to the subject at least one complex comprising a gold atom coordinated with a thiourea that has the following chemical structure:
- wherein R1 and R2 are hydrogen and wherein the anion is chloride, hexaflurophosphate (“PF6-”), or triflate.
Dependencies are inferred from the claim text.