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US 11,453,669 B2Granted
Polycyclic pyridone derivative
AssigneeShionogi & Co., Ltd.
InventorYoshiyuki Taoda
Life of this patent
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Abstract
The present invention provides a compound represented by the following formula (I): wherein, ring A is a substituted or unsubstituted non-aromatic heterocycle; ring C is a benzene ring or the like; Q is a 5-membered aromatic heterocycle or the like; each R1 is independently halogen or the like; L is substituted or unsubstituted alkylene; R3 is substituted or unsubstituted alkyl or the like; R4 is hydrogen or the like; and n is an integer of 1 to 3.
Claims18
A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof:
- wherein
- ring A is a substituted or unsubstituted non-aromatic heterocycle;
- ring C is a benzene ring or a pyridine ring;
- Q is a 5- or 6-membered aromatic heterocycle optionally substituted with one or more substituents selected from the group consisting of halogen, alkyl, haloalkyl, alkyloxy, haloalkyloxy, and alkylamino;
- each R1 is independently halogen, alkyl, haloalkyl, alkyloxy, cyano, or haloalkyloxy;
- L is substituted or unsubstituted alkylene;
- R3 is substituted or unsubstituted alkyl, substituted or unsubstituted non-aromatic carbocyclyl, or substituted or unsubstituted non-aromatic heterocyclyl;
- R4 is hydrogen, or substituted or unsubstituted alkyl;
- R3 and R4, or R3 and a substituent on ring A may be taken together with the adjacent atoms to form a substituted or unsubstituted non-aromatic heterocycle;
- and
- n is an integer of 1 to 3.
8 more elements
Dependencies are inferred from the claim text.