Thymoquinone/harmaline and related reaction products

One or more compounds of Structures X and XI below, and the derivatives, solvates, prodrugs, isomers, tautomers, esters, metal complexes, and salts thereof:

• where the six-membered A ring in each of the above structures is either phenyl or cyclohexadiene, the R1-R5 substituents may be attached at any valence-permitted position around the corresponding A rings, R1 is a C1-C4 alkyl group, R2 is H or a C1-C4 alkyl group, R3 and R4 are independently either —OH or ═O, R5 is isopropyl, and the dotted bond line refers to the fact that the bond between the 1 position on the A ring and the intermediate CH2 or CH group of the linker between the A ring and the six-membered, N-containing pyridyl ring may be either a single bond or a double bond, and in structure XI, the A rings may be the same or different.