Benzimidazole derivatives as adenosine receptor antagonists

A compound selected from the group consisting of:

• No.
• IUPAC-Name
• 2
• 4-Fluoro-N-(7-methoxy-4-phenyl-1H-benzoimidazol-2-yl)-
• benzamide,
• 3
• 2-Bromo-N-(7-methoxy-4-phenyl-1H-benzoimidazol-2-yl)-
• isonicotinamide,
• 4
• 2-Bromo-N-(4-bromo-7-methoxy-1H-benzoimidazol-2-yl)-
• isonicotinamide,
• 5
• 6-Bromo-N-(7-methoxy-4-phenyl-1H-benzoimidazol-2-yl)-
• nicotinamide,
• 6
• 6-Bromo-N-(4-bromo-7-methoxy-1H-benzoimidazol-2-yl)-
• nicotinamide,
• 7
• N-(7-Methoxy-4-phenyl-1H-benzoimidazol-2-yl)-2-morpholin-4-yl-
• isonicotinamide,
• 8
• N-(7-Methoxy-4-phenyl-1H-benzoimidazol-2-yl)-6-morpholin-4-yl-
• nicotinamide,
• 9
• N′-(7-Methoxy-4-phenyl-1H-benzoimidazol-2-yl)-N,N-dimethyl-
• formamidine,
• 10
• 4-Chloromethyl-N-(7-methoxy-4-phenyl-1H-benzoimidazol-2-yl)-
• benzamide,
• 11
• 4-Ethylaminomethyl-N-(7-methoxy-4-phenyl-1H-benzoimidazol-2-
• yl)-benzamide,
• 12
• 4-Hydroxy-4-methyl-piperidine-1-carboxylic acid (7-methoxy-4-
• phenyl-1H-benzoimidazol-2-yl)-amide,
• 13
• 4-Aminomethyl-N-(7-methoxy-4-phenyl-1H-benzoimidazol-2-yl)-
• benzamide,
• 15
• 4-Imidazol-1-ylmethyl-N-(7-methoxy-4-phenyl-1H-benzoimidazol-2-
• yl)-benzamide,
• 16
• 4-Hydroxy-4-methyl-piperidine-1-carboxylic acid (4-cyclohexyl-7-
• methoxy-1H-benzoimidazol-2-yl)-amide,
• 17
• N-(4-Cyclohexyl-7-methoxy-1H-benzoimidazol-2-yl)-2-morpholin-4-
• yl-isonicotinamide,
• 21
• 4-hydroxy-N-(7-methoxy-4-morpholino-1H-benzimidazol-2-yl)-4-
• methyl-piperidine-1-carboxamide,
• 22
• 4-Hydroxy-4-methyl-piperidine-1-carboxylic acid [7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 23
• N-(7-Methoxy-4-morpholin-4-yl-1H-benzoimidazol-2-yl)-2-
• morpholin-4-yl-isonicotinamide,
• 24
• 4-Hydroxy-4-methyl-piperidine-1-carboxylic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 26
• N-[7-Methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-
• 2-morpholin-4-yl-isonicotinamide,
• 28
• 4-Methyl-piperidine-1-carboxylic acid (7-methoxy-4-phenyl-1H-
• benzoimidazol-2-yl)-amide,
• 29
• N-[7-Methoxy-4-(tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-6-
• morpholin-4-yl-nicotinamide,
• 30
• 2-(3-Hydroxy-3-methyl-pyrrolidin-1-yl)-N-[7-methoxy-4-(1-methyl-
• 1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-isonicotinamide,
• 31
• 3-Hydroxy-3-methyl-pyrrolidine-1-carboxylic acid [7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 32
• 4-Hydroxy-4-trifluoromethyl-piperidine-1-carboxylic acid [7-
• methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-
• amide,
• 33
• 2-Oxa-7-aza-spiro[3.5]nonane-7-carboxylic acid [7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 34
• 4-Difluoromethyl-4-hydroxy-piperidine-1-carboxylic acid [7-
• methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-
• amide,
• 35
• 4-Hydroxymethyl-4-methyl-piperidine-1-carboxylic acid [7-methoxy-
• 4-(1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 36
• 4-Fluoromethyl-4-hydroxy-piperidine-1-carboxylic acid [7-methoxy-
• 4-(1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 37
• 4-Methoxy-piperidine-1-carboxylic acid [7-methoxy-4-(1-methyl-1H-
• pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 38
• 3-Oxa-9-aza-spiro[5.5]undecane-9-carboxylic acid [7-methoxy-4-
• (1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 39
• 4-Methyl-piperidine-1-carboxylic acid [7-methoxy-4-(1-methyl-1H-
• pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 40
• 4-Hydroxy-piperidine-1-carboxylic acid [7-methoxy-4-(1-methyl-1H-
• pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 41
• 4-Benzyl-4-hydroxy-piperidine-1-carboxylic acid [7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 42
• N-[4-methoxy-7-(1-methyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-
• c]pyridin-2-yl]-2-(morpholin-4-yl)pyridine-4-carboxamide,
• 43
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-oxa-6-azaspiro[3.4]octane-6-carboxamide,
• 44
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-oxo-1-oxa-3,8-diazaspiro[4.5]decane-8-carboxamide,
• 45
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide,
• 46
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]morpholine-4-carboxamide,
• 47
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-3-oxo-2,8-diazaspiro[4.5]decane-8-carboxamide,
• 48
• 4-[(dimethylamino)methyl]-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-
• yl)-1H-1,3-benzodiazol-2-yl]benzamide,
• 49
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-(methoxymethyl)benzamide,
• 50
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decane-8-carboxamide,
• 51
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-oxo-1,8-diazaspiro[4.5]decane-8-carboxamide,
• 52
• 4-(2-hydroxyethyl)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-
• 1,3-benzodiazol-2-yl]-1,2,3,6-tetrahydropyridine-1-carboxamide,
• 53
• 3-butyl-4-hydroxy-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-
• 1,3-benzodiazol-2-yl]piperidine-1-carboxamide,
• 54
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-phenoxypiperidine-1-carboxamide,
• 55
• 4-hydroxy-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-4-(pyridin-3-yl)piperidine-1-carboxamide,
• 56
• 4-hydroxy-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-3-(2-methylpropyl)piperidine-1-carboxamide,
• 57
• N-[4-(2,6-dimethylpyridin-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-2-(morpholin-4-yl)pyridine-4-carboxamide,
• 58
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-oxopiperidine-1-carboxamide,
• 60
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxamide,
• 62
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-methyl-5-oxo-1,4,9-triazaspiro[5.5]undecane-9-carboxamide,
• 63
• 4-fluoro-N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-benzodiazol-2-
• yl]benzamide,
• 64
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-6-oxaspiro[2.5]octane-1-carboxamide,
• 65
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-5-{3H-[1,2,3]triazolo[4,5-b]pyridin-3-yloxy}pyrazine-2-
• carboxamide,
• 66
• (chloromethyl)({2-[(1-{[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-
• 1,3-benzodiazol-2-yl]carbamoyl}-4-methylpiperidin-4-
• yl)oxy]ethyl})dimethylazanium hydrochloride,
• 67
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-7-oxa-2-azaspiro[4.5]decane-2-carboxamide,
• 68
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-8-oxa-2-azaspiro[4.5]decane-2-carboxamide,
• 69
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-oxa-7-azaspiro[4.4]nonane-7-carboxamide,
• 70
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-3-oxabicyclo[3.1.0]hexane-6-carboxamide,
• 71
• 4-[(1H-imidazol-1-yl)methyl]-N-[7-methoxy-4-(1-methyl-1H-pyrazol-
• 4-yl)-1H-1,3-benzodiazol-2-yl]benzamide,
• 72
• (1S,2S)-2-bromo-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-
• 1,3-benzodiazol-2-yl]cyclopropane-1-carboxamide,
• 73
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-5-(2-methoxyethoxy)pyrazine-2-carboxamide,
• 74
• 4-hydroxy-N-[7-methoxy-4-(pyridin-4-yl)-1H-1,3-benzodiazol-2-yl]-
• 4-methylpiperidine-1-carboxamide,
• 75
• 4-benzyl-4-hydroxy-N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-
• benzodiazol-2-yl]piperidine-1-carboxamide,
• 76
• 4-[(1H-imidazol-1-yl)methyl]-N-[7-methoxy-4-(morpholin-4-yl)-1H-
• 1,3-benzodiazol-2-yl]benzamide,
• 77
• N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-1-
• benzofuran-5-carboxamide,
• 78
• 4-hydroxy-N-{7-methoxy-4-[1-(oxan-2-yl)-1H-pyrazol-4-yl]-1H-1,3-
• benzodiazol-2-yl}-4-methylpiperidine-1-carboxamide,
• 79
• 4-hydroxy-N-[7-methoxy-4-(1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-methylpiperidine-1-carboxamide,
• 80
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-benzofuran-5-carboxamide,
• 81
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-5-(morpholin-4-yl)pyrazine-2-carboxamide,
• 82
• 4-hydroxy-N-[4-methoxy-7-(1-methyl-1H-pyrazol-4-yl)-3H-
• imidazo[4,5-c]pyridin-2-yl]-4-methylpiperidine-1-carboxamide,
• 83
• 4-benzyl-4-hydroxy-N-[4-methoxy-7-(1-methyl-1H-pyrazol-4-yl)-3H-
• imidazo[4,5-c]pyridin-2-yl]piperidine-1-carboxamide,
• 84
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1,2-oxazole-3-carboxamide,
• 85
• N-[7-methoxy-4-(pyridin-4-yl)-1H-1,3-benzodiazol-2-yl]-2-oxa-6-
• azaspiro[3.4]octane-6-carboxamide,
• 86
• 1-(1-chloro-3-hydroxypropan-2-yl)-N-[7-methoxy-4-(morpholin-4-
• yl)-1H-1,3-benzodiazol-2-yl]-1H-pyrazole-4-carboxamide,
• 87
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-6-(morpholin-4-yl)pyridazine-3-carboxamide,
• 88
• 4-[(dimethylamino)methyl]-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-
• benzodiazol-2-yl]benzamide,
• 89
• 4-[(dimethylamino)methyl]-N-[7-methoxy-4-(pyridin-4-yl)-1H-1,3-
• benzodiazol-2-yl]benzamide,
• 90
• 4-[(dimethylamino)methyl]-N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-
• benzodiazol-2-yl]benzamide,
• 91
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-6-(morpholin-
• 4-yl)pyridazine-3-carboxamide,
• 92
• 4-hydroxy-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-4-(prop-2-yn-1-yl)piperidine-1-carboxamide,
• 93
• N4-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 94
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-(trifluoromethoxy)benzamide,
• 95
• 2-bromo-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]pyridine-4-carboxamide,
• 96
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-methyl-1,3-oxazole-4-carboxamide,
• 97
• 4-[(1H-imidazol-1-yl)methyl]-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-
• benzodiazol-2-yl]benzamide,
• 98
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1,3-benzoxazole-5-carboxamide,
• 99
• 3-amino-4-hydroxy-N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-
• benzodiazol-2-yl]benzamide,
• 100
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-[(2-oxopyrrolidin-1-yl)methyl]benzamide,
• 101
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2,3-dihydro-1-benzofuran-5-carboxamide,
• 102
• 4-hydroxy-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-4-
• (prop-2-yn-1-yl)piperidine-1-carboxamide,
• 103
• 4-benzyl-4-hydroxy-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-
• benzodiazol-2-yl]piperidine-1-carboxamide,
• 104
• 2-[(3S)-3-hydroxy-3-methylpyrrolidin-1-yl]-N-[7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-yl]pyridine-4-
• carboxamide,
• 105
• 2-(4-hydroxy-4-methylpiperidin-1-yl)-N-[7-methoxy-4-(1-methyl-1H-
• pyrazol-4-yl)-1H-1,3-benzodiazol-2-yl]pyridine-4-carboxamide,
• 106
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-{2-oxa-7-azaspiro[4.4]nonan-7-yl}pyridine-4-carboxamide,
• 107
• 2-[(3R)-3-hydroxy-3-methylpyrrolidin-1-yl]-N-[7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-yl]pyridine-4-
• carboxamide,
• 108
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2,3-dihydro-
• 1-benzofuran-5-carboxamide,
• 109
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-3-(methoxymethyl)pyrrolidine-1-carboxamide,
• 110
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-oxa-7-
• azaspiro[4.4]nonane-7-carboxamide,
• 111
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-8-oxa-2-
• azaspiro[4.5]decane-2-carboxamide,
• 112
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-hexahydro-
• 1H-furo[3,4-c]pyrrole-5-carboxamide,
• 113
• (5R)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-7-oxa-2-azaspiro[4.5]decane-2-carboxamide,
• 114
• (5S)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-7-oxa-2-azaspiro[4.5]decane-2-carboxamide,
• 115
• (5S)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-2-oxa-7-azaspiro[4.4]nonane-7-carboxamide,
• 116
• (5R)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-2-oxa-7-azaspiro[4.4]nonane-7-carboxamide,
• 117
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-3-
• (methoxymethyl)pyrrolidine-1-carboxamide,
• 118
• 2-(4-hydroxy-4-methylpiperidin-1-yl)-N-[7-methoxy-4-(oxan-4-yl)-
• 1H-1,3-benzodiazol-2-yl]pyridine-4-carboxamide,
• 119
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-{2-oxa-7-
• azaspiro[4.4]nonan-7-yl}pyridine-4-carboxamide,
• 120
• 2-(4-fluorophenoxy)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-
• 1H-1,3-benzodiazol-2-yl]-2-methylpropanamide,
• 121
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-hexahydro-1H-furo[3,4-c]pyrrole-5-carboxamide,
• 122
• 2-(3-hydroxy-3-methylpyrrolidin-1-yl)-N-[7-methoxy-4-(oxan-4-yl)-
• 1H-1,3-benzodiazol-2-yl]pyridine-4-carboxamide,
• 123
• N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-2-oxa-7-
• azaspiro[4.4]nonane-7-carboxamide,
• 124
• 1-{[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]carbamoyl}piperidine-4-carboxylic acid,
• 125
• N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-8-oxa-2-
• azaspiro[4.5]decane-2-carboxamide,
• 126
• N1-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]piperidine-1,4-dicarboxamide,
• 127
• 4-(diethylamino)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-
• 1,3-benzodiazol-2-yl]benzamide,
• 128
• 4-hydroxy-N-{7-methoxy-4-[1-(2-methylpropyl)-1H-pyrazol-4-yl]-1H-
• 1,3-benzodiazol-2-yl}-4-methylpiperidine-1-carboxamide,
• 129
• N-[7-methoxy-4-(pyridin-4-yl)-1H-1,3-benzodiazol-2-yl]-8-oxa-2-
• azaspiro[4.5]decane-2-carboxamide,
• 130
• 2-(1-{[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-
• yl]carbamoyl}piperidin-4-yl)acetic acid,
• 131
• 4-hydroxy-N-[7-methoxy-4-(2-methylphenyl)-1H-1,3-benzodiazol-2-
• yl]-4-methylpiperidine-1-carboxamide,
• 132
• 2-(1-{[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-
• 2-yl]carbamoyl}piperidin-4-yl)acetic acid,
• 133
• N4-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-N1,N1-
• dimethylbenzene-1,4-dicarboxamide,
• 134
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-3-(2-methoxyethyl)pyrrolidine-1-carboxamide,
• 135
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-5-(morpholin-4-yl)pyridine-2-carboxamide,
• 136
• N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-1-
• methyl-1H-pyrazole-4-carboxamide,
• 137
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-3-(2-
• methoxyethyl)pyrrolidine-1-carboxamide,
• 138
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-4-[(2-
• oxopyrrolidin-1-yl)methyl]benzamide,
• 139
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-5-(morpholin-
• 4-yl)pyridine-2-carboxamide,
• 140
• (3R)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-3-(2-methoxyethyl)pyrrolidine-1-carboxamide,
• 141
• (3S)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-3-(2-methoxyethyl)pyrrolidine-1-carboxamide,
• 142
• 2-[(3R)-3-hydroxy-3-methylpyrrolidin-1-yl]-N-[7-methoxy-4-(oxan-4-
• yl)-1H-1,3-benzodiazol-2-yl]acetamide,
• 143
• 2-[(3S)-3-hydroxy-3-methylpyrrolidin-1-yl]-N-[7-methoxy-4-(oxan-4-
• yl)-1H-1,3-benzodiazol-2-yl]acetamide,
• 144
• N-[4-(4-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-4-
• hydroxy-4-methylpiperidine-1-carboxamide,
• 145
• tert-butyl 4-(4-{2-[(4-hydroxy-4-methylpiperidine-1-carbonyl)amino]-
• 4-methoxy-1H-1,3-benzodiazol-7-yl}-1H-pyrazol-1-yl)piperidine-1-
• carboxylate,
• 146
• 4-{[2-amino-7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-1-yl]methyl}benzoic acid,
• 147
• (3S)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-3-(methoxymethyl)pyrrolidine-1-carboxamide,
• 148
• (3R)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-3-(methoxymethyl)pyrrolidine-1-carboxamide,
• 149
• (5S)-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-oxa-7-
• azaspiro[4.4]nonane-7-carboxamide,
• 150
• (5R)-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-oxa-7-
• azaspiro[4.4]nonane-7-carboxamide,
• 151
• 4-hydroxy-N-{7-methoxy-4-[1-(3-methylbutyl)-1H-pyrazol-4-yl]-1H-
• 1,3-benzodiazol-2-yl}-4-methylpiperidine-1-carboxamide,
• 152
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-[(morpholin-4-yl)methyl]benzamide,
• 153
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-[(5R)-2-
• oxa-7-azaspiro[4.4]nonan-7-yl]pyridine-4-carboxamide,
• 154
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-[(5S)-2-
• oxa-7-azaspiro[4.4]nonan-7-yl]pyridine-4-carboxamide,
• 155
• N-[4-(3,6-dihydro-2H-pyran-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-4-hydroxy-4-methylpiperidine-1-carboxamide,
• 156
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-methyl-1H-1,2,3-triazole-4-carboxamide,
• 157
• 4-hydroxy-N-{4-methoxy-7-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-1H-
• 1,3-benzodiazol-2-yl}-4-methylpiperidine-1-carboxamide,
• 158
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-5-(2-methoxyethoxy)pyridine-2-carboxamide,
• 159
• 2-(1-{[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-
• 2-yl]carbamoyl}piperidin-3-yl)acetic acid,
• 160
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-methyl-1H-pyrazole-4-carboxamide,
• 161
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-(2-methoxyethyl)-1H-pyrazole-4-carboxamide,
• 162
• N5-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-N2,N2-dimethylpyridine-2,5-dicarboxamide,
• 163
• 4-hydroxy-N-[4-methoxy-1-methyl-7-(1-methyl-1H-pyrazol-4-yl)-1H-
• 1,3-benzodiazol-2-yl]-4-methylpiperidine-1-carboxamide,
• 164
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxamide,
• 165
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-methyl-1,3-thiazole-5-carboxamide,
• 167
• 1-(2-Hydroxy-ethyl)-1H-pyrazole-4-carboxylic acid [7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 168
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide,
• 169
• 1-Methyl-1H-pyrazole-4-carboxylic acid [7-methoxy-4-(1-methyl-
• 1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 170
• 5-Methyl-isoxazole-4-carboxylic acid [7-methoxy-4-(1-methyl-1H-
• pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 171
• 5-Cyclopropyl-isoxazole-4-carboxylic acid [7-methoxy-4-(1-methyl-
• 1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 172
• 1-Cyano-cyclopropanecarboxylic acid [7-methoxy-4-(1-methyl-1H-
• pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 173
• Thiazole-5-carboxylic acid [7-methoxy-4-(1-methyl-1H-pyrazol-4-
• yl)-1H-benzoimidazol-2-yl]-amide,
• 174
• 5,6,7,8-Tetrahydro-imidazo[1,2-a]pyridine-3-carboxylic acid [7-
• methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-
• amide,
• 175
• 4-(4-Methyl-piperazin-1-yl)-but-2-ynoic acid [7-methoxy-4-(1-
• methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 179
• (S)-3-Methanesulfonyl-pyrrolidine-1-carboxylic acid [7-methoxy-4-
• (1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 180
• (S)-3-Fluoro-pyrrolidine-1-carboxylic acid [7-methoxy-4-(1-methyl-
• 1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 181
• (S)-3-Cyano-pyrrolidine-1-carboxylic acid [7-methoxy-4-(1-methyl-
• 1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 182
• (R)-3-Dimethylaminomethyl-pyrrolidine-1-carboxylic acid [7-
• methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-benzoimidazol-2-yl]-
• amide,
• 183
• 5-Methyl-isoxazole-4-carboxylic acid (7-methoxy-4-morpholin-4-yl-
• 1H-benzoimidazol-2-yl)-amide,
• 184
• N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-1-(2-
• methoxyethyl)-1H-1,2,3-triazole-4-carboxamide,
• 185
• 1-Methyl-1H-[1,2,3]triazole-4-carboxyylic acid (7-methoxy-4-
• morpholin-4-yl-1H-benzoimidazol-2-yl)-amide,
• 186
• Pyridine-2,5-dicarboxylic acid 2-dimethylamide 5-{[7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide},
• 187
• 1-(2-Methoxy-ethyl)-1H-pyrazole-4-carboxylic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 188
• N-[7-Methoxy-4-(tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-4-
• morpholin-4-ylmethyl-benzamide,
• 189
• N-[7-Methoxy-4-(tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-4-
• (4-methyl-piperazin-1-ylmethyl)-benzamide,
• 190
• 1-Methyl-1H-pyrazole-4-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 191
• 5-Methyl-isoxazole-4-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 192
• 5-Cyclopropyl-isoxazole-4-carboxylic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 193
• 1-(2-Methoxy-ethyl)-1H-[1,2,3]triazole-4-carboylic acid [7-
• methoxy-4-(tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 194
• 1-Methyl-1H-[1,2,3]triazole-4-carboylic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 195
• 1-Cyano-cyclopropanecarboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 196
• Thiazole-5-carboxylic acid [7-methoxy-4-(tetrahydro-pyran-4-yl)-
• 1H-benzoimidazol-2-yl]-amide,
• 197
• 2-Methyl-oxazole-5-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 198
• 2-Methyl-thiazole-5-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 199
• Imidazo[1,2-a]pyridine-3-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 200
• 5-Amino-2H-[1,2,4]triazole-3-carboxylic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 201
• (S)-3-Methanesulfonyl-pyrrolidine-1-carboxylic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 202
• (S)-3-Fluoro-pyrrolidine-1-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 203
• (S)-3-Cyano-pyrrolidine-1-carboxylic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 204
• (R)-3-Dimethylaminomethyl-pyrrolidine-1-carboxylic acid [7-
• methoxy-4-(tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 205
• Pyrazolo[1,5-a]pyridine-3-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 206
• 1H-[1,2,4]Triazole-3-carboxylic acid [7-methoxy-4-(tetrahydro-
• pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 207
• 5,6,7,8-Tetrahydro-imidazo[1,2-a]pyridine-3-carboxylic acid [7-
• methoxy-4-(tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 208
• 2,3-Dimethyl-3H-imidazole-4-sulfonic acid [7-methoxy-4-
• (tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-amide,
• 209
• 1-[7-Methoxy-4-(tetrahydro-pyran-4-yl)-1H-benzoimidazol-2-yl]-3-
• thiazol-2-ylmethyl-urea,
• 210
• N-[7-methoxy-4-(morpholin-4-yl)-1H-1,3-benzodiazol-2-yl]-1-
• methyl-1H-1,2,3-triazole-4-carboxamide,
• 211
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-1-(2-
• methoxyethyl)-1H-1,2,3-triazole-4-carboxamide,
• 212
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-1-methyl-1H-
• 1,2,3-triazole-4-carboxamide,
• 213
• 1-cyano-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]cyclopropane-1-carboxamide,
• 214
• N5-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-N2,N2-
• dimethylpyridine-2,5-dicarboxamide,
• 215
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-2-methyl-1,3-oxazole-5-carboxamide,
• 216
• N-[4-(azepan-1-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-4-hydroxy-
• 4-methylpiperidine-1-carboxamide,
• 217
• N-[4-(3-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-4-
• hydroxy-4-methylpiperidine-1-carboxamide,
• 218
• N-[4-(2-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-4-
• hydroxy-4-methylpiperidine-1-carboxamide,
• 219
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1,3-thiazole-5-carboxamide,
• 220
• (3R)-3-methanesulfonyl-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-
• yl)-1H-1,3-benzodiazol-2-yl]pyrrolidine-1-carboxamide,
• 221
• (3S)-3-fluoro-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]pyrrolidine-1-carboxamide,
• 222
• 4-hydroxy-N-[7-methoxy-4-(1-methyl-6-oxo-1,6-dihydropyridin-3-
• yl)-1H-1,3-benzodiazol-2-yl]-4-methylpiperidine-1-carboxamide,
• 223
• (3S)-3-(aminomethyl)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-
• 1H-1,3-benzodiazol-2-yl]pyrrolidine-1-carboxamide,
• 224
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-1-methyl-1H-
• pyrazole-4-carboxamide,
• 225
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-1-(2-
• methoxyethyl)-1H-pyrazole-4-carboxamide,
• 226
• 1-cyano-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-
• yl]cyclopropane-1-carboxamide,
• 227
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-methyl-1,3-
• thiazole-5-carboxamide,
• 228
• 3-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-1-[(1,3-
• thiazol-2-yl)methyl]urea,
• 229
• N-{7-[1-(difluoromethyl)-1H-pyrazol-4-yl]-4-methoxy-1H-1,3-
• benzodiazol-2-yl}-4-hydroxy-4-methylpiperidine-1-carboxamide,
• 230
• 4-hydroxy-N-(4-methoxy-7-{1-[2-(2-methoxyethoxy)ethyl]-1H-
• pyrazol-4-yl}-1H-1,3-benzodiazol-2-yl)-4-methylpiperidine-1-
• carboxamide,
• 231
• 4-hydroxy-N-{4-methoxy-7-[1-(pyridin-2-yl)-1H-pyrazol-4-yl]-1H-
• 1,3-benzodiazol-2-yl}-4-methylpiperidine-1-carboxamide,
• 232
• N-[7-methoxy-4-(1-propylcyclopropyl)-1H-1,3-benzodiazol-2-yl]-1-
• methyl-1H-pyrazole-4-carboxamide,
• 233
• N-[4-(hexan-3-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-methyl-
• 1H-pyrazole-4-carboxamide,
• 234
• N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-2-methyl-1,3-
• oxazole-5-carboxamide,
• 235
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide,
• 236
• 4-hydroxy-N-{4-methoxy-7-[3-(2-methoxyethoxy)phenyl]-1H-1,3-
• benzodiazol-2-yl}-4-methylpiperidine-1-carboxamide,
• 237
• 4-hydroxy-N-(4-methoxy-7-{1-[(pyridin-3-yl)methyl]-1H-pyrazol-4-
• yl}-1H-1,3-benzodiazol-2-yl)-4-methylpiperidine-1-carboxamide,
• 238
• 4-hydroxy-N-{7-[1-(2-hydroxy-2-methylpropyl)-1H-pyrazol-4-yl]-4-
• methoxy-1H-1,3-benzodiazol-2-yl}-4-methylpiperidine-1-
• carboxamide,
• 239
• N-[4-(3-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-
• methyl-1H-pyrazole-4-carboxamide,
• 240
• N4-[4-(3-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-N1,N1-
• dimethylbenzene-1,4-dicarboxamide,
• 241
• 4-hydroxy-N-{4-methoxy-7-[1-(oxolan-3-yl)-1H-pyrazol-4-yl]-1H-
• 1,3-benzodiazol-2-yl}-4-methylpiperidine-1-carboxamide,
• 242
• N4-[4-(2-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-N1,N1-
• dimethylbenzene-1,4-dicarboxamide,
• 243
• N-[4-(2-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-
• methyl-1H-pyrazole-4-carboxamide,
• 244
• N-[4-methoxy-1-methyl-7-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-
• benzodiazol-2-yl]-1-methyl-1H-pyrazole-4-carboxamide,
• 245
• tert-butyl 3-(4-{2-[(4-hydroxy-4-methylpiperidine-1-carbonyl)amino]-
• 4-methoxy-1H-1,3-benzodiazol-7-yl}-1H-pyrazol-1-yl)azetidine-1-
• carboxylate,
• 246
• N-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-5-oxopyrrolidine-3-carboxamide,
• 247
• 3-[7-methoxy-4-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-2-
• yl]-1-[(1,3-thiazol-2-yl)methyl]urea,
• 248
• 4-(2,5-dioxopyrrolidin-1-yl)-N-[7-methoxy-4-(1-methyl-1H-pyrazol-
• 4-yl)-1H-1,3-benzodiazol-2-yl]benzamide,
• 249
• 1-[(3R,4S)-4-fluoropyrrolidin-3-yl]-3-[7-methoxy-4-(1-methyl-1H-
• pyrazol-4-yl)-1H-1,3-benzodiazol-2-yl]urea,
• 250
• 4-(2,5-dioxopyrrolidin-1-yl)-N-[7-methoxy-4-(oxan-4-yl)-1H-1,3-
• benzodiazol-2-yl]benzamide,
• 251
• tert-butyl (3S,4R)-3-fluoro-4-({[7-methoxy-4-(1-methyl-1H-pyrazol-
• 4-yl)-1H-1,3-benzodiazol-2-yl]carbamoyl}amino)pyrrolidine-1-
• carboxylate,
• 252
• N4-[7-methoxy-4-(1,2,3,6-tetrahydropyridin-4-yl)-1H-1,3-
• benzodiazol-2-yl]-N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 253
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1H-imidazole-4-
• carboxamide,
• 254
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1-methyl-1H-
• imidazole-5-carboxamide,
• 255
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-2-methyl-1H-
• imidazole-4-carboxamide,
• 256
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1,3-thiazole-5-
• carboxamide,
• 257
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-2-methyl-1,3-
• thiazole-5-carboxamide,
• 258
• 2-amino-N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1,3-
• thiazole-5-carboxamide,
• 259
• N4-[7-methoxy-4-(pyridin-3-yl)-1H-1,3-benzodiazol-2-yl]-N1,N1-
• dimethylbenzene-1,4-dicarboxamide,
• 260
• N-[7-methoxy-4-(pyridin-3-yl)-1H-1,3-benzodiazol-2-yl]-1-methyl-
• 1H-pyrazole-4-carboxamide,
• 261
• N4-[4-(2,5-dihydrofuran-3-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-
• N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 262
• N4-[4-(3,6-dihydro-2H-pyran-4-yl)-5-fluoro-7-methoxy-1H-1,3-
• benzodiazol-2-yl]N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 263
• 3-{[dimethyl(oxo)-lambda6-sulfanylidene]amino}-N-[7-methoxy-4-
• (oxan-4-yl)-1H-1,3-benzodiazol-2-yl]benzamide,
• 264
• N-[4-(3,6-dihydro-2H-pyran-4-yl)-5-fluoro-7-methoxy-1H-1,3-
• benzodiazol-2-yl]-1-methyl-1H-pyrazole-4-carboxamide,
• 265
• N-[7-(3-fluorophenyl)-4-methoxy-1H-1,3-benzodiazol-2-yl]-1H-
• imidazole-4-carboxamide,
• 266
• N-[4-methoxy-7-(pyridin-4-yl)-1H-1,3-benzodiazol-2-yl]-1H-
• imidazole-4-carboxamide,
• 267
• N-{4-methoxy-7-[3-(2-methoxyethoxy)phenyl]-1H-1,3-benzodiazol-
• 2-yl}-1H-imidazole-4-carboxamide,
• 268
• N-[4-methoxy-7-(pyridin-3-yl)-1H-1,3-benzodiazol-2-yl]-1H-
• imidazole-4-carboxamide,
• 269
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1,3-dimethyl-1H-
• pyrazole-4-carboxamide,
• 270
• 4-hydroxy-N-(7-methoxy-4-{1H-pyrrolo[2,3-b]pyridin-4-yl}-1H-1,3-
• benzodiazol-2-yl)-4-methylpiperidine-1-carboxamide,
• 271
• 4-hydroxy-N-[4-(1H-indazol-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-4-methylpiperidine-1-carboxamide,
• 272
• 4-hydroxy-N-[4-(1H-indol-6-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-4-methylpiperidine-1-carboxamide,
• 273
• 4-hydroxy-N-[7-methoxy-4-(1-methyl-1H-indazol-5-yl)-1H-1,3-
• benzodiazol-2-yl]-4-methylpiperidine-1-carboxamide,
• 274
• 4-hydroxy-N-[7-methoxy-4-(3-methyl-1H-indazol-5-yl)-1H-1,3-
• benzodiazol-2-yl]-4-methylpiperidine-1-carboxamide,
• 275
• 4-hydroxy-N-(4-{imidazo[1,2-a]pyridin-7-yl}-7-methoxy-1H-1,3-
• benzodiazol-2-yl)-4-methylpiperidine-1-carboxamide,
• 277
• N4-[5-fluoro-7-methoxy-4-(oxan-4-yl)-1H-1,3-benzodiazol-2-yl]-
• N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 278
• N-(7-methoxy-4-{1H-pyrrolo[2,3-b]pyridin-4-yl}-1H-1,3-benzodiazol-
• 2-yl)-1-(2-methoxyethyl)-1H-pyrazole-4-carboxamide,
• 279
• N-[4-(1H-indazol-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-(2-
• methoxyethyl)-1H-pyrazole-4-carboxamide,
• 280
• N-[4-(1H-indo1-6-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-(2-
• methoxyethyl)-1H-pyrazole-4-carboxamide,
• 281
• N-[7-methoxy-4-(1-methyl-1H-indazol-5-yl)-1H-1,3-benzodiazol-2-
• yl]-1-(2-methoxyethyl)-1H-pyrazole-4-carboxamide,
• 282
• N-[7-methoxy-4-(3-methyl-1H-indazol-5-yl)-1H-1,3-benzodiazol-2-
• yl]-1-(2-methoxyethyl)-1H-pyrazole-4-carboxamide,
• 283
• N-[4-(2,3-dihydro-1H-indo1-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-1-(2-methoxyethyl)-1H-pyrazole-4-carboxamide,
• 284
• N2-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-N5,N5-
• dimethylpyridine-2,5-dicarboxamide,
• 285
• 4-(2,5-dioxopyrrolidin-1-yl)-N-(7-methoxy-4-phenyl-1H-1,3-
• benzodiazol-2-yl)benzamide,
• 286
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)imidazo[1,2-
• a]pyridine-3-carboxamide,
• 287
• 4,4-difluoro-N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-
• yl)pipendine-1-carboxamide,
• 288
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)imidazo[1,2-
• b]pyridazine-3-carboxamide,
• 289
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)imidazo[1,2-
• a]pyrimidine-3-carboxamide,
• 290
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-2-(pyridin-4-yl)-
• 1H-imidazole-4-carboxamide,
• 291
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-5H,6H,7H,8H-
• imidazo[1,2-a]pyridine-3-carboxamide,
• 292
• N-[4-(2,3-dihydro-1H-indo1-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-4-hydroxy-4-methylpiperidine-1-carboxamide,
• 293
• N1-(4-methoxy-7-phenyl-1H-1,3-benzodiazol-2-yl)-N4-
• propylbenzene-1,4-dicarboxamide,
• 294
• N-(4-methoxy-7-phenyl-1H-1,3-benzodiazol-2-yl)-4-(4-
• methylpiperazine-1-carbonyl)benzamide,
• 295
• N4-(4-methoxy-7-phenyl-1H-1,3-benzodiazol-2-yl)-N1-(2-
• methoxyethyl)-N1-methylbenzene-1,4-dicarboxamide,
• 296
• N1-[2-(dimethylamino)ethyl]-N4-(4-methoxy-7-phenyl-1H-1,3-
• benzodiazol-2-yl)-N1-methylbenzene-1,4-dicarboxamide,
• 297
• N4-(4-methoxy-7-phenyl-1H-1,3-benzodiazol-2-yl)-N1-methyl-N1-
• propylbenzene-1,4-dicarboxamide,
• 298
• N-(4-methoxy-7-phenyl-1H-1,3-benzodiazol-2-yl)-4-(morpholine-4-
• carbonyl)benzamide,
• 299
• N-[4-methoxy-7-(2-methylpyridin-4-yl)-1H-1,3-benzodiazol-2-yl]-
• 1H-imidazole-4-carboxamide,
• 300
• N-(5-cyano-7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1-
• methyl-1H-pyrazole-4-carboxamide,
• 301
• N-(4-{imidazo[1,2-a]pyridin-7-yl}-7-methoxy-1H-1,3-benzodiazol-2-
• yl)-1-(2-methoxyethyl)-1H-pyrazole-4-carboxamide,
• 302
• N-[4-(1H-indo1-5-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-(2-
• methoxyethyl)-1H-pyrazole-4-carboxamide,
• 303
• 4-hydroxy-N-[4-(1H-indo1-5-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-4-methylpiperidine-1-carboxamide,
• 304
• N-[4-(1H-indo1-7-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-(2-
• methoxyethyl)-1H-pyrazole-4-carboxamide,
• 305
• 4-hydroxy-N-[4-(1H-indo1-7-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-4-methylpiperidine-1-carboxamide,
• 306
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1-methyl-1H-
• pyrazole-4-carboxamide,
• 307
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-1-(2-
• methoxyethyl)-1H-pyrazole-4-carboxamide,
• 308
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-2-methyl-1,3-
• oxazole-5-carboxamide,
• 309
• N4-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-N1,N1-
• dimethylbenzene-1,4-dicarboxamide,
• 310
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-8-oxa-2-
• azaspiro[4.5]decane-2-carboxamide,
• 311
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-4-[(2-
• oxopyrrolidin-1-yl)methyl]benzamide,
• 312
• N1-(2-hydroxyethyl)-N4-(4-methoxy-7-phenyl-1H-1,3-benzodiazol-
• 2-yl)benzene-1,4-dicarboxamide,
• 313
• N4-[7-methoxy-4-(1,4-oxazepan-4-yl)-1H-1,3-benzodiazol-2-yl]-
• N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 314
• N-[4-(3,6-dihydro-2H-pyran-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]cyclopropanecarboxamide,
• 315
• N-[7-methoxy-4-(pyridin-3-yl)-1H-1,3-benzodiazol-2-
• yl]cyclopropanecarboxamide,
• 316
• N4-[4-(4-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-N1,N1-
• dimethylbenzene-1,4-dicarboxamide,
• 317
• 4-(2,5-dioxopyrrolidin-1-yl)-N-[4-(4-fluorophenyl)-7-methoxy-1H-
• 1,3-benzodiazol-2-yl]benzamide,
• 318
• N-[4-(4-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-
• methyl-1H-pyrazole-4-carboxamide,
• 319
• N4-[4-(2,6-dimethoxypyridin-3-yl)-7-methoxy-1H-1,3-benzodiazol-
• 2-yl]-N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 320
• N-[4-(2,6-dimethoxypyridin-3-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]cyclopropanecarboxamide,
• 321
• N-[7-methoxy-4-(pyridin-3-yl)-1H-1,3-benzodiazol-2-yl]-2-methyl-
• 1,3-oxazole-5-carboxamide,
• 322
• N-[4-(2,5-dihydrofuran-3-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-2-
• methyl-1,3-oxazole-5-carboxamide,
• 323
• N-[4-(4-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-2-
• methyl-1,3-oxazole-5-carboxamide,
• 324
• N4-[4-(3,6-dihydro-2H-pyran-4-yl)-7-methoxy-1H-1,3-benzodiazol-
• 2-yl]-N1,N1-dimethylbenzene-1,4-dicarboxamide,
• 325
• N-[4-(3,6-dihydro-2H-pyran-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-1-methyl-1H-pyrazole-4-carboxamide,
• 326
• (4-{2-[(4-hydroxy-4-methylpiperidine-1-carbonyl)amino]-7-methoxy-
• 1H-1,3-benzodiazol-4-yl}morpholin-2-yl)methyl carbamate,
• 327
• (1-{2-[(4-hydroxy-4-methylpiperidine-1-carbonyl)amino]-7-methoxy-
• 1H-1,3-benzodiazol-4-yl}piperidin-3-yl)methyl cyanate,
• 328
• (1-{2-[(4-hydroxy-4-methylpiperidine-1-carbonyl)amino]-7-methoxy-
• 1H-1,3-benzodiazol-4-yl}piperidin-3-yl)methyl carbamate,
• 329
• N-(7-methoxy-4-phenyl-1H-1,3-benzodiazol-2-yl)-2-oxa-8-
• azaspiro[4.5]decane-8-carboxamide,
• 330
• N-[4-(1H-indo1-6-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1H-
• imidazole-4-carboxamide,
• 331
• N-[4-(1H-indo1-6-yl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-1-methyl-
• 1H-pyrazole-4-carboxamide,
• 332
• N-[4-(4-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-8-oxa-2-
• azaspiro[4.5]decane-2-carboxamide,
• 333
• N-[4-(3,6-dihydro-2H-pyran-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-8-oxa-2-azaspiro[4.5]decane-2-carboxamide,
• 334
• N-[4-(3,6-dihydro-2H-pyran-4-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]-4-[(2-oxopyrrolidin-1-yl)methyl]benzamide,
• 335
• N-[4-(4-fluorophenyl)-7-methoxy-1H-1,3-benzodiazol-2-yl]-4-[(2-
• oxopyrrolidin-1-yl)methyl]benzamide,
• 336
• N-[4-(1H-indo1-6-yl)-7-methoxy-1H-1,3-benzodiazol-2-
• yl]cyclopropanecarboxamide,
• and physiologically acceptable salts, solvates, prodrugs and stereoisomers thereof, including mixtures thereof in all ratios.