A device for opening/closing a top box or a suitcase for motorcycles and for coupling/releasing such top box/suitcase relative to a support structure fastened to the motorcycle, said top box/suitcase comprising a lower shell, forming the top box body, and an upper shell, forming the cover of the top box and which is hinged to the lower shell, on the bottom portion of the lower shell reversible constraining means to a support element being provided fastened to the motorcycle and a plate being associated on the outer surface of the lower shell, on which plate the following is obtained:
- a first button for releasing the top box from the support plate, operatively connected to said reversible constraining means,
- a second button for opening the upper shell relative to the lower shell, operatively connected to coupling means hinged to the plate and able to selectively engage a corresponding coupling means integral with the upper shell;
- and
- a lock block,
- a first under-lock body rigidly rotatably constrained to said lock block and which can be rotatably actuated to switch from a configuration of simultaneous lock of said first button and said second button to a configuration of simultaneous unlock of said first button and said second button and vice versa;
- a second under-lock body which can be rotatably actuated to switch from a configuration of locking said second button to a configuration of unlocking said second button and vice versa,
- wherein said first under-lock body is configured to drive in rotation said second under-lock body while switching from said configuration of simultaneous lock of said first button and said second button to said configuration of simultaneous unlock of said first button and said second button.