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US 11,452,823 B2Granted
Breath-enhanced jet nebulizer
AssigneesInspirx, Inc., The Research Foundation for The State University of New York
InventorsRohinton D. Toddywala, Vijay Shukla, Gerald C. Smaldone
Life of this patent
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Abstract
A breath-enhanced jet nebulizer is configured with a low liquid retention reservoir and a narrow liquid delivery passage to efficiently and efficiently aerosolize small drug volumes with minimal waste. Aerosol particles are directed through aerosol passage for delivery, although larger liquid particles are directed away from the aerosol outlet and recycled to the liquid reservoir.
Claims28
An apparatus for forming an aerosol comprising:
- a main housing comprising a substantially cylindrical inner volume;
- an axially-oriented gas inlet nozzle integral with the main housing and comprising a gas orifice at a distal end thereof;
- an annular fluid reservoir disposed between an outer wall of the gas inlet nozzle and a sloped inner wall of the main housing;
- a flue disposed within the inner volume, the flue comprising a sleeve portion slideably engaged with the gas inlet nozzle and defining an annular liquid flow passage therebetween, wherein an annular aerosol passage is disposed between an outer wall of the flue and an inner wall of the main housing;
- primary baffle axially aligned with and spaced apart from the gas orifice;
- a first secondary baffle extending radially from an outer surface of the flue through an arc in a plane perpendicular to a central axis of the flue and into the aerosol passage, the first secondary baffle comprising a substantially planar ledge forming a bottom surface thereof,
- a second secondary baffle axially displaced from the first secondary baffle and extending radially from the outer surface of the flue through the same arc and into the aerosol passage, the second secondary baffle comprising an arcuate cross section having a bottom surface angled relative to the plane;
- and
- a cap comprising a one-way inhalation valve, wherein the cap is sealably engaged with the main housing, wherein the one-way inhalation valve opens inwardly to allow ambient air to enter the main housing and closes to prevent aerosol from escaping the main housing.
6 more elements
Dependencies are inferred from the claim text.