Apparatuses, systems, and methods for the treatment of a tissue site with negative pressure and oxygen

A system for providing treatment to a tissue site, the system comprising:

• a tissue interface configured to transport fluid to and from the tissue site;
• a cover configured to provide a sealed space that includes the tissue interface;
• a negative-pressure source fluidly coupled to the tissue interface and configured to provide negative pressure;
• a hyperoxic fluid source fluidly coupled to the tissue interface and configured to provide a hyperoxic fluid;
• a valve fluidly coupled between the hyperoxic fluid source and the tissue interface;
• and
• a controller operatively coupled to the negative-pressure source and operatively coupled to the valve, the controller configured to:
• provide a first therapy interval by controlling an operating parameter of the negative-pressure source to maintain the sealed space at a first range of negative pressure,
• send a first signal to open the valve at a conclusion of the first therapy interval to allow negative pressure at the tissue interface to draw the hyperoxic fluid to the tissue interface, and
• send a second signal to close the valve upon negative pressure at the tissue interface reaching a second range of negative pressure.