Wound dressing material comprising fibrillated accellular dermis matrix and biodegradeable polymer, and preparation method therefor
AssigneesCg Bio Co., Ltd., The Asan Foundation
InventorsHee Jun Park, Hyun Seung Ryu, Joon Pio Hong, Jun Hyuk Seo, Jong Ha Park, Soon Gee Hong, Hak Su Jang, So Myoung Lee, Bo Young Yoo
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Abstract
The present invention relates to a wound dressing material comprising a fibrillated acellular dermis matrix and a biodegradable polymer aqueous solution and, more specifically, to: a wound dressing material comprising 5-20 wt % of a fibrillated acellular dermis matrix, 0.5-5 wt % of a biodegradable polymer, and 75-94.5 wt % of water; and a preparation method therefor.
Claims10
A wound dressing comprising 5 to 20% by weight of fiberized acellular dermal matrix, 0.5 to 5% by weight of biocompatible polymer and 75 to 94.5% by weight of water,
- wherein the fiberized acellular dermal matrix is prepared by pulverizing acellular dermal matrix with a cutting mill,
- the fiberized acellular dermal matrix is in the form of cotton, and
- the fiberized acellular dermal matrix has a fiber length of 200 to 1,000 μm,
- wherein the biocompatible polymer is gelatin, hyaluronic acid, collagen, poloxamer, or a mixture thereof, and
- wherein the wound dressing is in a dosage form of a paste.
A method for preparing a wound dressing which comprises:
- pulverizing acellular dermal matrix by using a cutting mill to obtain fiberized acellular dermal matrix;
- dissolving biocompatible polymer in water to obtain a biocompatible polymer aqueous solution;
- mixing the fiberized acellular dermal matrix and the biocompatible polymer aqueous solution to obtain a mixture comprising 5 to 20% by weight of fiberized acellular dermal matrix, 0.5 to 5% by weight of biocompatible polymer and 75 to 94.5% by weight of water;
- and
- sterilizing the mixture,
- wherein the fiberized acellular dermal matrix is in the form of cotton and has a fiber length of 200 to 1,000 μm,
- the biocompatible polymer is gelatin, hyaluronic acid, collagen, poloxamer, or a mixture thereof, and
- the wound dressing is in the form of a paste.
Dependencies are inferred from the claim text.