Homogeneous ophthalmic composition
OwnerRandal Davisinventor
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Abstract
This application is directed to a homogeneous solution of an aqueous, topical composition useful for the treatment of infection and/or for the treatment of inflammation due to trauma to tissue. Specifically, this application relates to a homogeneous, aqueous composition of a quinolone antibiotic and an anti-inflammatory agent.
Claims13
A composition, comprising an aqueous, homogeneous solution of about 0.5% by weight moxifloxacin, about 0.035% by weight bromfenac, about 0.1% by weight dexamethasone phosphate, about 0.01% by weight edetate disodium dihydrate, hydroxyethyl cellulose to adjust viscosity, about 0.005% by weight benzalkonium chloride, about 0.05% by volume polysorbate 80, and about 1.8% by volume glycerin, wherein the composition has a pH in the range of about 8.20 to about 8.25 and remains a solution during topical application to an eye of a patient.
A composition, comprising an aqueous, homogeneous solution of about 0.5% by weight moxifloxacin, about 0.035% by weight bromfenac, about 0.1% by weight dexamethasone phosphate, about 0.01% by weight edetate disodium dihydrate, about 0.085% w/v hydroxyethyl cellulose, about 0.005% by weight benzalkonium chloride, and about 0.05% by volume polysorbate 80, wherein the composition has a pH in the range of about 8.2 to about 8.5 and remains a solution during topical application to an eye of a patient.
A composition comprising an aqueous, homogeneous solution of about 0.5% by weight moxifloxacin, about 0.035% by weight bromfenac, about 0.1% by weight dexamethasone phosphate, about 0.01% by weight edetate disodium dihydrate, hydroxyethyl cellulose, about 0.005% by weight benzalkonium chloride, and about 1.8% by volume glycerin, and about 0.05% by volume polysorbate 80, wherein the solution has a pH in the range of about 8.20 to about 8.25.
A composition comprising an aqueous, homogeneous solution of moxifloxacin, bromfenac sodium sesquihydrate, edetate disodium dihydrate, hydroxyethyl cellulose, benzalkonium chloride, hydrochloric acid to adjust pH, sodium hydroxide to adjust pH, and glycerin wherein the solution has a pH in the range of about 8.20 to about 8.25 and remains a solution during topical application to an eye of a patient.
Dependencies are inferred from the claim text.