Combination therapy for treating cancer
AssigneeEpizyme, Inc.
InventorsMaria Alejandra Raimondi, Dorothy Brach
Life of this patent
Estimating the term…
Abstract
The disclosure relates to methods, compounds for use and medicaments for the treatment of cancer comprising administering to a subject in need thereof a first agent in a therapeutically effective amount and one or more second agents each in a therapeutically effective amount. In some embodiments, the first agent comprises an EZH2 inhibitor. In certain embodiments, the first agent is tazemetostat or a pharmaceutically acceptable salt thereof and the methods of the disclosure are used to treat lung cancer, e.g., non-small cell lung cancer.
Claims18
A method for treatment of non-small cell lung cancer (NSCLC) comprising administering to a subject in need thereof:
- (a) an amount of an EZH2 inhibitor, and
- (b) an anaplastic lymphoma kinase (ALK) inhibitor.
Dependencies are inferred from the claim text.