US 11,452,605 B2 · Magnetic actuated microscaffold for minimally invasive osteochondral regeneration

Abstract

Provided is a magnetically actuated microscaffold for minimal invasive osteochondral regeneration. More particularly, provided is a composition for cartilage regeneration, a microscaffold for cartilage regeneration, in which magnetic particles and cartilage regeneration cells are loaded on the surface of or within a 3-dimensional porous microstructure composed of a biodegradable polymer and having a diameter of 200-300 μm; and a microscaffold for bone regeneration, in which magnetic particles and bone regeneration cells are loaded on the surface of or within a 3-dimensional porous microstructure composed of a biodegradable polymer and having a diameter of 700-900 μm.

Claims12

Dependent claims

A composition for cartilage regeneration, comprising:

a porous microscaffold for cartilage regeneration, in which magnetic particles and cartilage regeneration cells are loaded on the surface of or within a 3-dimensional porous microstructure composed of a biodegradable polymer and having a diameter of 200-300 μm;
and
a porous microscaffold for bone regeneration, in which magnetic particles and bone regeneration cells are loaded on the surface of or within a 3-dimensional porous microstructure composed of a biodegradable polymer and having a diameter of 700-900 μm, wherein the porous microscaffold for cartilage regeneration has an inner pore size of 45-115 μm and the porous microscaffold for bone regeneration has an inner pore size of 85-130 μm.

Dependencies are inferred from the claim text.

Facts

Application

15/975,311Filed 9 May 2018

Priority

KR 10-2018-004409516 Apr 2018

Published

US 2019/0314156 A117 Oct 2019

Granted

27 Sep 2022

Term ends

Not estimatedThe source records don’t support an estimate.

Classification28 codes

A61F 2/30756
Joints: cartilage endoprostheses
A61K 31/728
Glycosaminoglycans, i.e. mucopolysaccharides: hyaluronic acid
A61L 27/16
Macromolecular materials: obtained by reactions only involving carbon-to-carbon unsaturated bonds
A61L 27/18
Macromolecular materials: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

Magnetic actuated microscaffold for minimally invasive osteochondral regeneration

Life of this patent

Magnetic actuated microscaffold for minimally invasive osteochondral regeneration

Life of this patent

Abstract

Claims12