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US 11,452,597 B2Granted
Replacement heart valve
AssigneeEdwards Lifesciences CardiAQ LLC
InventorsArshad Quadri, J. Brent Ratz
Life of this patent
Estimating the term…
Abstract
A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve. The valve body has an upstream end and a downstream end, and a diameter at the downstream end is greater than a diameter at the upstream end.
Claims20
A method of delivering a replacement valve to a native valve of a heart and securing the replacement valve relative to a native valve annulus, the method comprising:
- delivering the replacement valve to the native valve annulus while the replacement valve is in a radially compacted state, the replacement valve comprising:
- an expandable frame having a proximal end ending at a proximalmost end and a distal end ending at a distalmost end;
- a valve body positioned within a lumen of the expandable frame;
- and
- a plurality of distal anchors extending proximally from the distal end of the expandable frame, wherein at least a portion of each distal anchor is positioned radially outwardly from the frame;
- and
- expanding the replacement valve within the native valve annulus to an expanded state, wherein in the expanded state:
- the replacement valve has a distal cross-sectional diameter at the distalmost end of the expandable frame that is greater than a proximal cross-sectional diameter at the proximalmost end of the expandable frame, the expandable frame only decreasing or remaining constant in cross-sectional diameter from the distalmost end to the proximalmost end;
- and
- wherein, after expanding the replacement valve within the native valve annulus, at least one of the plurality of distal anchors extends between chordae tendineae of the native valve, and
- wherein the plurality of distal anchors are sized to contact tissue on a ventricular side of the native valve when the replacement valve is expanded within the native valve annulus.
8 more elements
A method of delivering a replacement valve to a native valve of a heart and securing the replacement valve relative to a native valve annulus, the method comprising:
- delivering the replacement valve to the native valve annulus while the replacement valve is in a radially compacted state, the replacement valve comprising:
- an expandable frame configured to engage the native valve annulus;
- a valve body positioned within a lumen of the expandable frame, the valve body comprising a plurality of valve leaflets configured to open to allow flow in a first direction and engage one another so as to close and not allow flow in a second direction opposite the first direction;
- and
- a plurality of distal anchors extending proximally from a downstream end of the expandable frame, wherein at least a portion of each distal anchor is positioned radially outwardly from the expandable frame,
- wherein the valve body has an upstream end and a downstream end, and a diameter at the downstream end is greater than a diameter at the upstream end,
- wherein the replacement heart valve comprises an elongate upstream portion maintaining an inflow diameter, a transition portion disposed adjacent the upstream portion of the valve body that flares outwardly so that the diameter increases, and a downstream portion disposed adjacent the transition portion;
- and
- expanding the replacement valve within the native valve annulus to an expanded state,
- wherein the plurality of distal anchors are sized to contact tissue on a ventricular side of the native valve when the replacement valve is expanded within the native valve annulus.
7 more elements
A method of delivering a replacement valve to a native valve of a heart and securing the replacement valve relative to a native valve annulus, the method comprising:
- delivering the replacement valve to the native valve annulus while the replacement valve is in a radially compacted state, the replacement valve comprising:
- an expandable frame having a proximal end ending at a proximalmost end and a distal end ending at a distalmost end;
- a valve body positioned within a lumen of the expandable frame;
- and
- a plurality of distal anchors extending proximally from the distal end of the expandable frame, wherein at least a portion of each distal anchor is positioned radially outwardly from the frame;
- and
- expanding the replacement valve within the native valve annulus to an expanded state, wherein in the expanded state:
- the replacement valve has a distal cross-sectional diameter at the distalmost end of the expandable frame that is greater than a proximal cross-sectional diameter at the proximalmost end of the expandable frame,
- wherein, after expanding the replacement valve within the native valve annulus, at least one of the plurality of distal anchors extends between chordae tendineae of the native valve, and
- wherein the expandable frame comprises a proximal anchoring portion positioned radially outwardly from the frame and sized to contact tissue on an atrial side of the native valve when the replacement valve is expanded within the native valve annulus.
7 more elements
Dependencies are inferred from the claim text.