Miniaturized sensing probe and manufacturing method thereof

A miniaturized sensing probe, comprising:

• a probe substrate comprising a probe part and a circuit connection part;
• a needle unit used to accommodate the probe part of the probe substrate, wherein the needle unit has a plurality of openings disposed on a wall of the needle unit along a longitudinal direction of the needle unit;
• a plurality of sensors respectively disposed on a plurality of positions, which are exposed by the plurality of the openings, on the probe part and electrically connecting the circuit connection part, wherein the plurality of sensors perform sensing functions when the needle unit is placed into an analyte and transmit a sensing signal through the circuit connection part;
• and
• a plurality of waterproof elements disposed between the openings to define a plurality of spaces for respectively accommodating the plurality of the sensors to prevent fluid from flowing between the plurality of the sensors.