Evaluation method for the coverage of a coating on a contact lens surface
AssigneeAlcon Inc.
InventorHarald Bothe
Life of this patent
Estimating the term…
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AssigneeAlcon Inc.
InventorHarald Bothe
Estimating the term…
The invention provides a method for determining whether a coated contact lens is completely covered by a covalently bonded coating, comprising the steps of (1) providing a coated polyvinylalcohol-based hydrogel contact lens wherein the polyvinylalcohol-based hydrogel lens body is composed of a polymer comprising at least 50% by mole of repeating units of vinyl alcohol, comprising a lubricious coating covalently attached to the lens body, (2) contacting the coated polyvinylalcohol-based hydrogel contact lens with an aqueous solution of a hydrophilic marker polymer for obtaining a treated contact lens, the hydrophilic marker polymer having reactive groups of in which R1 is methyl or ethyl and R2 is hydrogen or a C1-C4 alkyl and a dye tag moiety, at a pH of 4.0 or less for a contacting time to covalently attach the marker polymer onto the coated polyvinylalcohol-based hydrogel contact lens through 6-membered acetal rings, (3) determining whether marker polymer is (covalently) attached to the surface of the treated contact lens.
A method for determining whether a coated polyvinylalcohol-based hydrogel contact lens is completely covered by a covalently bonded lubricous coating, comprising the steps of:
Dependencies are inferred from the claim text.