Image atlas systems and methods
AssigneeBeckman Coulter, Inc.
InventorsJun Yang, Jon Tindel
Life of this patent
Estimating the term…
Abstract
In some embodiments, a process and system are provided for generating a user interface for classification of a sample image of a cell that includes receiving a sample image of a sample particle from a biological sample and selecting reference images that each portray a reference particle of a biological sample. The reference images can be ordered based on similarity and the reference images can be selected based on the order. The first selected reference image can be aligned with the sample image and expanded such that the adjacent edges of the reference image and sample image are the same. The expanded image can be dynamically filled. The sample image and the expanded reference image can be displayed in a user interface.
Claims6
A method, comprising:
- receiving, at a computer system, a sample visual image of a sample particle from a biological sample;
- selecting, by the computer system, a plurality of reference images from a database of reference images, each reference image of the plurality of reference images being a reference image of a reference particle from a plurality of reference particles from one or more biological samples;
- determining, by the computer system, an order of the plurality of reference images based on a similarity of each reference image to the sample image;
- selecting, by the computer system, a first reference image from the plurality of reference images based on the determined order;
- physically aligning, by the computer system, the first reference image with the sample image;
- dynamically filling, by the computer system, a physical background image of the aligned first reference image;
- and
- displaying, by the computer system, the sample image and the dynamically filled and aligned first reference image in a user interface;
- wherein the determining the order of the plurality of reference images comprises:
- comparing, by the computer system, the sample image with each reference image of the plurality of reference images;
- and
- determining, by the computer system, the similarity of each reference image to the sample image;
- wherein the comparing the sample image with each reference image of the plurality of reference images comprises:
- generating, by the computer system, a feature vector for each of the reference images of the plurality of reference images and the sample image;
- and
- calculating, by the computer system, a distance metric for each reference image of the plurality of reference images by comparing the feature vectors of each of the plurality of reference images with the feature vectors of the sample image.
Dependencies are inferred from the claim text.