A control circuit (27) for a waste heat recovery system (2) for a heat engine (36), wherein the waste heat recovery system (2) comprises at least one evaporator (21) for converting waste heat from exhaust gas (31, 31a) generated by the heat engine (36) into a working medium (23), at least one expansion machine (24), which can be driven by the working medium (23), at least one condenser (25) for condensing the working medium (23a) expanded in the expansion machine (24) into a liquid state (23b) and at least one delivery device (26) for increasing a pressure of the condensed working medium (23b) and delivering it into the evaporator (21), wherein the control circuit (27) controls at least one control variable which controls (a) an energy transfer from the exhaust gas (31, 31a) to the working medium (23b), (b) an energy transfer from the working medium (23c) to the expansion machine (24), or both (a) and (b), wherein the control circuit (27) is configured to regulate a specific enthalpy hW, a temperature TW, or both the specific enthalpy hW and the temperature TW of the working medium (23c) entering the expansion machine (24) to a set value hW,S, TW,S, or to set values hW,S and TW,S, wherein the set value hW,S, TW,S, or both, as applicable, depends on the pressure pW of the working medium (23c) entering the expansion machine (24), and a prediction module (28a) is provided, which is designed to precalculate a future development of the specific enthalpy hW, of the temperature TW or the pressure pW, on the basis of a model (2a) and at least one set of state variables of the waste heat recovery system (2).