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US 11,447,562 B2Granted
RP215 chimeric antigen receptor construct and methods of making and using same
AssigneeChi-Yu Gregory Lee
InventorChi-Yu Gregory Lee
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Abstract
A chimeric antigen receptor (CAR) having an antigen binding domain capable of binding to CA215. The antigen binding domain can have a binding affinity and specificity similar to the RP215 antibody. Methods of making and using such CARs are provided. The CARs can be used to treat cancer.
Claims6
A nucleotide vector capable of expressing an RP215 CAR, the nucleotide vector encoding a polypeptide having the amino acid sequence of SEQ ID NO:7.
An isolated nucleic acid molecule encoding a polypeptide having the amino acid sequence of SEQ ID NO:7.
An RP215 CAR comprising a polypeptide having the amino acid sequence of SEQ ID NO:7.
Dependencies are inferred from the claim text.