US 11,447,541 B1 · Anti-coronavirus antibodies and methods of use

Anti-coronavirus antibodies and methods of use

AssigneesAbCellera Biologies Inc., The United States of America, as represented by the Secretary, Department of Health and Human Svcs.

InventorsKathryn Westendorf, Stefanie Zentelis, Krithika Muthuraman, Kevin Jepson, Ester Falconer, John Mascola, Barney Graham, Kizzmekia Corbett, Julie Ledgerwood, Lingshu Wang, Olubukola Abiona, Wei Shi, Wing-pui Kong, Yi Zhang, Bryan Edward Jones, Denisa Foster, Julian Davies, Qing Chai, Christopher Carl Frye, Ganapathy Gopalrathnam, Jörg Hendle, John Michael Sauder, Jeffrey Streetman Boyles, Anna Pustilnik

Life of this patent

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Abstract

Antibodies that bind SARS-CoV Spike protein, SARS-CoV-2 Spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.

Claims26

Dependent claims

An antibody that specifically binds to a SARS-CoV-2 spike protein, wherein the antibody comprises three CDRs of a heavy chain variable region (VH) set forth as SEQ ID NO:

4949 and three CDRs of a light chain variable region (VL) set forth as SEQ ID NO:
4950, wherein the antibody has an IgG1m3 allotype.

Dependencies are inferred from the claim text.

Facts

Application

17/354,476Filed 22 Jun 2021 · continuation

Priority

9 Mar 2020

Granted

20 Sep 2022

Term ends

Not estimatedThe source records don’t support an estimate.

Classification28 codes

A61K 39/215
Viral antigens: coronaviridae, e.g. avian infectious bronchitis virus
A61K 47/02
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents…:…
A61K 47/183
Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids: amino acids, e.g. glycine, EDTA or…
A61K 47/26
Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite: carbohydrates, e.g. sugar alcohols,…

Family

Application62/987,313Us provisional application · filed 9 Mar 2020

Application63/010,999Us provisional application · filed 16 Apr 2020

Application63/030,530Us provisional application · filed 27 May 2020

Application63/036,089Us provisional application · filed 8 Jun 2020

Application63/080,351Us provisional application · filed 18 Sep 2020

Application63/085,042Us provisional application · filed 29 Sep 2020

Application63/116,483Us provisional application · filed 20 Nov 2020

Application17/192,243Parent of this continuation · filed 4 Mar 2021

US 2022/0356229 A1Published application

US 11,447,541 B1This patent

From the US filing history. Foreign family members aren’t listed.