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US 11,447,539 B2Granted
PD-L1 binding fibronectin type III domains
AssigneeJanssen Biotech, Inc.
InventorsMichael Diem, Rebecca Hawkins, Steven Jacobs, Manuel Sepulveda
Life of this patent
Estimating the term…
Abstract
FN3 domains that specifically bind to PD-L1, their conjugates, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making and using them are useful in therapeutic and diagnostic applications.
Claims13
A protein comprising an amino acid sequence that is at least 95% identical to a sequence selected from the group consisting of SEQ ID NOs:
- 34, 35, 36, 37, 38, 39, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, and 124.
Dependencies are inferred from the claim text.