Diterpene glycosides containing an ent-atisene core, compositions and methods
AssigneeThe Coca-Cola Company
InventorsIndra Prakash, Gil Ma
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Abstract
Novel diterpene glycosides containing ent-atisene cores are provided herein. Compositions and consumables comprising the novel diterpene glycosides are also provided herein. Methods of enhancing the sweetness and/or flavor of consumables using the novel diterpene glycosides, methods of preparing compositions and consumables comprising the novel diterpene glycosides and methods of purifying the novel diterpene glycosides are also provided.
Claims18
A diterpene glycoside of Formula I:
- wherein when y is a double bond, X is C, Y is CH2, z is absent and Z is absent;
- when y is single bond, z is a single bond, X is C and Y and Z are each independently selected from methyl and hydroxyl;
- and
- R1 and R2 are each independently selected from a monosaccharide and an oligosaccharide.
A method for enhancing the flavor of a consumable, comprising (i) providing a consumable comprising at least one flavor ingredient and (ii) adding a diterpene glycoside of Formula I to the consumable to provide a consumable with enhanced flavor, wherein the diterpene glycoside of Formula I in present in the consumable with enhanced flavor at a concentration below its flavor recognition threshold, and wherein Formula I is:
- wherein:
- when y is a double bond, X is C, Y is CH2, z is absent and Z is absent;
- when y is single bond, z is a single bond, X is C and Y and Z are each independently selected from methyl and hydroxyl;
- and
- R1 and R2 are each independently selected from a monosaccharide and oligosaccharide.
A method for enhancing the sweetness of a consumable, comprising (i) providing a consumable comprising at least one sweet ingredient and (ii) adding a diterpene glycoside of Formula I to the consumable to provide a consumable with enhanced sweetness, wherein the diterpene glycoside of Formula I in present in the consumable with enhanced sweetness at a concentration below its flavor recognition threshold, and wherein Formula 1 is:
- wherein:
- when y is a double bond, X is C, Y is CH2, z is absent and Z is absent;
- when y is single bond, z is a single bond, X is C and Y and Z are each independently selected from methyl and hydroxyl;
- and
- R1 and R2 are each independently selected from a monosaccharide and oligosaccharide.
A method for purifying a diterpene glycoside of Formula I:
- wherein:
- when y is a double bond, X is C, Y is CH2, z is absent and Z is absent;
- when y is single bond, z is a single bond, X is C and Y and Z are each independently selected from methyl and hydroxyl;
- and
- R1 and R2 are each independently selected from a monosaccharide and oligosaccharide;
- comprising:
- (i) passing a solution comprising a source material comprising a diterpene glycoside of Formula I through a HPLC column, and
- (ii) eluting fractions comprising the diterpene glycoside of Formula I to provide a purified diterpene glycoside of Formula 1 having a purity of about 50% or greater.
Dependencies are inferred from the claim text.