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US 11,447,440 B2Granted
Treprostinil monohydrate crystals and methods for preparation thereof
AssigneeChirogate International Inc.
InventorsShih-Yi Wei, Jian-Bang Jheng, Chun Hsieh
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Abstract
Novel crystalline forms of Treprostinil monohydrate, a mixture including the same, and preparation methods thereof.
Claims10
A crystalline Treprostinil monohydrate Form I, characterized by having an X-ray powder diffraction (XRPD) pattern comprising its two strongest characteristic peaks at the following 2θ reflection angles:
- 5.43±0.2°, and 10.87±0.2°.
A crystalline Treprostinil monohydrate Form II, characterized by having an XRPD pattern comprising its two strongest characteristic peaks at the following 2θ reflection angles:
- 5.19±0.2°, and 10.40±0.2°.
Dependencies are inferred from the claim text.