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US 11,446,658 B2Granted
Microfluidic device
AssigneeEpigem Limited
InventorsTimothy George Ryan, Philip Summersgill, Simon Allen, Andrew Baker
Life of this patent
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Abstract
A microfluidic device has a cavity in which a functionalized mesh is arranged in a layered configuration to provide a high surface area. The cavity is housed in a body that is easily configured for sample flow to concentrate the analyte, heat release of the analyte from the mesh, and elution of the released analyte. The microfluidic device can be used in a variety of applications by functionalizing the mesh with a suitable affinity media.
Claims23
A microfluidic device having a cavity defining microfluidic volume, comprising:
- a plurality of meshes provided in the cavity, each mesh having a plurality of apertures and an outer surface;
- the plurality of meshes arranged in a layered configuration with the apertures of adjacent layers offset with respect to one another to define a plurality of circuitous pathways therethrough, wherein the apertures in each mesh are arranged in a grid, whereby the grid of one mesh is rotated with respect to the grid of an adjacent mesh;
- the outer surface of each mesh having a functionalizing material applied thereto;
- wherein each mesh is formed of nickel.
1 more element
Dependencies are inferred from the claim text.