Rotary platform for cell lysing and purification and method of use
AssigneeSiemens Healthcare Diagnostics Inc.
InventorsJason Bryant, Eric Yeaton, Dan Harris, Josiah Hackendorf, Steven Allen, Mark Talmer
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AssigneeSiemens Healthcare Diagnostics Inc.
InventorsJason Bryant, Eric Yeaton, Dan Harris, Josiah Hackendorf, Steven Allen, Mark Talmer
Estimating the term…
Magnetic beads having cell components of interest are translated between a sequence of processing wells in a tray without need for pipetting. The circular tray contains one or more sequences of wells each interconnected by a respective channel. The tray is rotated about a central axis and a magnet, an agitator, and a heater provided external to the tray enable magnetic bead translation, mixing, and incubation, respectively. The magnet proximate a well forms a cluster of beads. Manipulation of the tray in rotation and elevation results in translation of the cluster from one well, through a channel, and into an adjacent well. The well containing a cluster may be rotationally positioned in front of the agitator, the agitator extended into contact with the well, followed by mechanical agitation. The heater, disposed beneath the tray, may accept a well lowered thereto for selective heating.
A rotary platform comprising:
The rotary platform of 2, wherein the outer surface of each well outer surface narrows in a direction distal from the tray.
A system comprising:
Dependencies are inferred from the claim text.