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US 11,446,488 B2Granted
Kidney treatment
AssigneeLeonhardt Ventures LLC
InventorHoward J. Leonhardt
Life of this patent
Estimating the term…
Abstract
Described is a low voltage, pulsed electrical stimulation device for controlling expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells and treating a subject's kidneys.
Claims18
A method of treating a subject's kidney(s), the method comprising:
- stimulating muscle(s) of the subject for 30 minutes with a bioelectric stimulator programmed to produce and producing a bioelectric signal, which bioelectric signal stimulates said muscle(s) to increase expression and/or release of Klotho polypeptide so as to treat the kidney(s), wherein the bioelectric signal comprises:
- a biphasic pulse at (within 15%) 20 Hz, 0.1 V, and a 7.8 ms pulse duration.
Dependencies are inferred from the claim text.