Methods and apparatus for treating a respiratory disorder

An oxygen concentrator apparatus comprising:

• at least two canisters;
• gas separation adsorbent disposed in the at least two canisters, wherein the gas separation adsorbent separates at least some nitrogen from air in the at least two canisters to produce oxygen enriched gas;
• a compression system, the compression system comprising:
• a compressor coupled to at least one of the canisters, wherein the compressor compresses air during operation;
• and
• a motor coupled to the compressor, wherein the motor drives operation of the compressor;
• an accumulator coupled to one or more of the canisters, wherein oxygen enriched gas produced in one or more of the canisters is passed into the accumulator during use;
• and
• a controller, including one or more processors, and a set of valves coupled to the controller, the controller configured to control operation of the set of valves to (a) produce oxygen enriched gas into the accumulator and (b) release the produced oxygen enriched gas from the accumulator in at least one bolus, the controller further configured to:
• generate a minimum inhalation flow profile of a user based on a size parameter of the user;
• determine one or more control parameters characterizing the at least one bolus based on the generated minimum inhalation flow profile;
• and
• generate a bolus release control signal according to the determined one or more control parameters, the generated bolus release control signal configured to cause the at least one bolus to be released from the accumulator.

An oxygen concentrator apparatus comprising:

• at least two canisters;
• gas separation adsorbent disposed in the at least two canisters, wherein the gas separation adsorbent separates at least some nitrogen from air in the at least two canisters to produce oxygen enriched gas;
• a compression system, the compression system comprising:
• a compressor coupled to at least one of the canisters, wherein the compressor compresses air during operation;
• and
• a motor coupled to the compressor, wherein the motor drives operation of the compressor;
• an accumulator coupled to one or more of the canisters, wherein oxygen enriched gas produced in one or more of the canisters is passed into the accumulator during use;
• and
• a controller, including one or more processors, and a set of valves coupled to the controller, the controller configured to control operation of the set of valves to (a) produce oxygen enriched gas into the accumulator and (b) release, in pulsed oxygen delivery mode, the produced oxygen enriched gas from the accumulator in at least one bolus, the controller further configured to:
• derive a delivery envelope of parameters of a potential bolus of oxygen enriched gas based on a size parameter of a user;
• determine one or more control parameters characterizing a deliverable bolus of oxygen enriched gas so that the one or more parameters are constrained within the delivery envelope;
• and
• generate a bolus release control signal according to the determined one or more control parameters, the bolus release control signal for controlling release of a bolus of oxygen enriched gas from the accumulator.

An oxygen concentrator apparatus comprising:

• at least two canisters;
• gas separation adsorbent disposed in the at least two canisters, wherein the gas separation adsorbent separates at least some nitrogen from air in the at least two canisters to produce oxygen enriched gas;
• a compression system, the compression system comprising:
• a compressor coupled to at least one of the canisters, wherein the compressor compresses air during operation;
• and
• a motor coupled to the compressor, wherein the motor drives operation of the compressor;
• an accumulator coupled to one or more of the canisters, wherein oxygen enriched gas produced in one or more of the canisters is passed into the accumulator during use;
• and
• a controller, including one or more processors, and a set of valves coupled to the controller, the controller configured to control operation of the set of valves to (a) produce oxygen enriched gas into the accumulator and (b) release the produced oxygen enriched gas from the accumulator, the controller further configured to:
• estimate a tidal volume for a user based on a size parameter of the user and a breathing rate of the user;
• and
• generate an inhalation flow profile for the user from the tidal volume and an inspiratory time for the user.

A respiratory therapy apparatus comprising:

• a controller, including one or more processors, configured to control one or more operations of the respiratory therapy apparatus to produce a respiratory therapy, wherein the controller is configured to:
• estimate a resting energy expenditure of a user based on a size parameter of the user;
• estimate a respiratory parameter for the user based on the estimated resting energy expenditure;
• and
• control an operation of the respiratory therapy apparatus based on the estimated respiratory parameter.