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US 11,446,391 B2Granted
Amphiphilic dye-coated inorganic nanoparticle clusters
AssigneeThe Trustees of the University of Pennsylvania
InventorsAndrew Tsourkas, Jayesh Thawani, Ahmad Amirshaghaghi, Lesan Yan, Zhiliang Cheng
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Abstract
The invention relates to amphiphilic dye-coated inorganic nanoparticle clusters and uses thereof. Specifically, the invention relates to cyanine and/or cyclic tetrapyrrole dye-coated metallic nanoparticle clusters for use in medical imaging and treatments.
Claims22
A nanocluster comprising:
- a plurality of inorganic nanoparticles or of hydrophobic polymers, wherein said nanoparticles or said hydrophobic polymers are coated by one or more amphiphilic dyes, and wherein said one or more amphiphilic dyes are capable of solubilizing said nanoparticles or said hydrophobic polymers in an aqueous solvent.
Dependencies are inferred from the claim text.