Compositions, methods and uses comprising teneurin C-terminal associated peptide -1 (TCAP-1) for enhancing muscle performance

A method for enhancing and/or restoring muscle function in a patient in need thereof comprising administering to a patient in need thereof a therapeutically effective amount of a teneurin c-terminal associated peptide-1 (TCAP-1 peptide), or a pharmaceutically acceptable salt or ester thereof or a pharmaceutical composition comprising same, wherein the amino acid sequence of said TCAP-1 peptide consists of:

• (i) an amino acid sequence having at least 95% identity to an amino acid sequence selected from the group consisting of SEQ ID NOs:
• 1, 2 or 3;
• optionally wherein:
• (a) the carboxy terminal end of said peptide is amidated or comprises an amidation signal sequence;
• and/or
• (b) when the amino terminal amino acid of said peptide is a glutamine.