Method of treatment
AssigneeHexima Limited
InventorsNicole Louise van der Weerden, Marilyn Anne Anderson
Life of this patent
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Abstract
The present disclosure relates to the control of fungal infection of horn-like envelopes covering dorsal and terminal phalanges in humans and animals and related cerebral protrusions in animals as well as keratin comprising material on surfaces of humans and animals. Agents and natural and synthetic formulations and extracts useful for the control of fungal infection of these envelopes and related protrusions and keratin comprising material are also encompassed by the subject disclosure. In an embodiment, the present disclosure teaches the treatment of fungal infection of nails and in particular onychomycosis in humans.
Claims9
A topical formulation for treating fungal infection, the formulation comprising a plant defensin consisting of an amino acid sequence selected from the group consisting of SEQ ID NO:25, SEQ ID NO:26 and SEQ ID NO:27 or a variant thereof having at least 80% similarity to any of the foregoing, wherein said variant comprises an N-terminal alanine residue and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.