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US 11,446,316 B2Granted
Galactooligosaccharides for preventing injury and/or promoting healing of the gastrointestinal tract
AssigneeAbbott Laboratories
InventorsSteven R. Davis, Jomay Chow
Life of this patent
Estimating the term…
Abstract
Disclosed are nutritional compositions including galactooligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and/or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the galactooligosaccharides are also disclosed.
Claims8
A method of stimulating a healing response of the gastrointestinal tract of an individual, the method comprising:
- identifying an individual having an injured gastrointestinal tract;
- and
- administering to the individual a nutritional composition comprising a galacto-oligosaccharide in a concentration of from 8 kg/1000 kg of the nutritional composition to 160 kg/1000 kg of the nutritional composition;
- wherein the gastrointestinal tract is injured as a result of at least one of antibiotic therapy, radiation therapy, chemotherapy, surgery, enteric infection, inflammatory bowel disease, colitis, and chronic stress.
1 more element
A method of stimulating a healing response of the gastrointestinal tract of an individual, the method comprising:
- identifying an individual having an injured gastrointestinal tract;
- and administering to the individual a nutritional composition comprising protein, fat, carbohydrate, and a galacto-oligosaccharide in a concentration of from 8 g/L of the nutritional composition to 160 g/L of the nutritional composition;
- wherein the healing response comprises increased expression of at least one mucin-associated protein and the mucin-associated protein is selected from the group consisting of TFF3, MUC-2, and RELMb.
Dependencies are inferred from the claim text.