Compounds that modulate von Willebrand factor levels and their use in the treatment of blood disorders
AssigneeSociete des Produits Nestle S.A.
InventorsJasna Klicic Badoux, Amy Melissa Pooler, Claus Rieker
Life of this patent
Estimating the term…
Abstract
The present invention relates to a compound having the structure of Formula (I) for use in the prevention or treatment of a blood disorder, in particular by the modulation of von Willebrand factor levels. A nutraceutical product or food product comprising the compound of the invention 5 are also provided.
Claims5
A method for reducing a risk and/or severity of or treatment of a blood disorder in a patient in need thereof, the method comprising administering to the patient a triterpene compound selected from the group consisting of celastrol, pristimerin, and tingenone, and the blood disorder is selected from the group consisting of von Willebrand Factor disease, thrombosis, hemostasis, hypercoagulation, abnormal blood flow, endothelial cell dysfunction, and combinations thereof.
Dependencies are inferred from the claim text.