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AssigneeKorea Research Institute of Bioscience and Biotechnology
InventorsBo Yeon Kim, Joonsung Hwang, Nak Kyun Soung, Jong Seog Ahn, Kyung Ho Lee, Jiyun Mun, Srinivasrao Ganipisetti, Hyunjoo Cha, Mija Ahn, Hee Gu Lee, Jae-Hyuk Jang, In Ja Ryoo, Sung-Kyun Ko
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The present invention relates to a composition for preventing, alleviating or treating inflammatory diseases, comprising, as an active ingredient, an acylhydrazone derivative compound, a stereoisomer thereof or a pharmaceutically acceptable salt thereof. an acylhydrazone derivative compound, a stereoisomer thereof or a pharmaceutically acceptable salt thereof, of the present invention, effectively inhibits inflammatory cytokines and inflammatory signaling pathways, thereby effectively alleviating symptoms of inflammatory diseases such as dermatitis. Therefore, the composition according to the present invention may be effectively used for the prevention, alleviation or treatment of inflammatory diseases.
A method for treating dermatitis, comprising administering to a subject in need thereof an effective amount of a compound represented by a following Chemical Formula 1, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof:
A method for alleviating skin inflammation caused by dermatitis, comprising applying to a subject in need thereof an effective amount of a compound represented by a following Chemical Formula 1, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof:
Dependencies are inferred from the claim text.