Penetrating topical pain relief compositions and methods of use
AssigneeTech Swerve LLC
InventorJohn M. Guynn
Life of this patent
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Abstract
A topical composition includes a cannabinoid, a terpenoid, and a skin penetration system that includes dimethyl sulfoxide (DMSO) and at least one compatibilizer. The composition may be in the form of an emulsion that further contains water and at least one fatty component. The composition can be used to reduce or eliminate pain by topical application to an affected region of the body. The composition provides localized pain relief by providing a focused quantity of cannabinoid in the region of the pain instead of distributing the cannabinoid systemically and/or delivering it to the brain or central nervous system.
Claims20
A composition for topical pain relief, comprising:
- 0.003% to about 5% by weight of a cannabinoid component;
- 0.002% to about 4% by weight of a terpenoid component including a plurality of terpenoids selected from the group consisting of α-pinene, β-pinene, camphene, β-myrcene, humulene, α-bisabolol, β-caryophyllene, linalool, camphor, limonene, ocimene, α-phellandrene, 1,8-ceneole, eucalyptol, γ-terpinene, terpineol, fenchol, phytol, nerolidol, geranyl acetate, sabinene, p-cymene, β-phellandrene, valencene, borneol, isoborneol, geraniol, δ-3-carene, and terpinolene, wherein the ratio (w/w) of total terpenoids to total cannabinoids is in a range of about 1:10 to about 5:1;
- 30% to 80% by weight of dimethyl sulfoxide (DMSO);
- water;
- a fatty component;
- and
- a compatibilizer,
- wherein the ratio of the DMSO to the compatibilizer is greater than about 1:1 by weight,
- wherein the composition comprises greater than 40% by combined weight of the DMSO, water, and compatibilizer.
A composition for topical pain relief, comprising:
- 0.05-10% by weight of at least one of CBD or THC;
- 0.002% to about 4% by weight of a plurality of terpenoids selected from the group consisting of α-pinene, β-pinene, camphene, β-myrcene, humulene, α-bisabolol, β-caryophyllene, linalool, camphor, limonene, ocimene, α-phellandrene, 1,8-ceneole, eucalyptol, γ-terpinene, terpineol, fenchol, phytol, nerolidol, geranyl acetate, sabinene, p-cymene, β-phellandrene, valencene, borneol, isoborneol, geraniol, δ-3-carene, and terpinolene, wherein the ratio (w/w) of total terpenoids to total cannabinoids is in a range of about 1:10 to about 5:1;
- a skin penetration system comprising dimethyl sulfoxide (DMSO) and a compatibilizer, wherein the composition comprises 35% to 75% by weight of the DMSO, wherein the ratio of DSMO to compatibilizer is greater than 1:1 by weight;
- water;
- and
- a fatty component,
- wherein the composition is an emulsion,
- wherein the composition contains greater than 45% by combined weight of the DMSO, compatibilizer, and water.
A composition for targeted topical pain relief, comprising:
- 0.05% to 10% by combined weight of cannabidiol (CBD), tetrahydrocannabinol (THC), and optionally one or more of tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), cannabinol (CBN), cannabigerol (CBG), cannabichchromene (CBC), tetrahydrocannabivarin (THCV), cannabicyclol (CBL), cannabidivarin (CBDV), cannabichromevarin (CBCV), or cannabigerovarin (CBGV);
- 0.002% to about 4% by weight of a terpenoid component including a plurality of terpenoids selected from the group consisting of α-pinene, β-pinene, camphene, β-myrcene, humulene, α-bisabolol, β-caryophyllene, linalool, camphor, limonene, ocimene, α-phellandrene, 1,8-ceneole, eucalyptol, γ-terpinene, terpineol, fenchol, phytol, nerolidol, geranyl acetate, sabinene, p-cymene, β-phellandrene, valencene, borneol, isoborneol, geraniol, δ-3-carene, and terpinolene, wherein the ratio (w/w) of total terpenoids to total cannabinoids is in a range of about 1:5 to about 2:1;
- 40% to 70% by weight of dimethyl sulfoxide (DMSO);
- water;
- a fatty component;
- and
- a compatibilizer,
- wherein the ratio of the DMSO to the compatibilizer is greater than about 1:1, by weight,
- wherein the composition contains greater than 50% by combined weight of the DMSO, compatibilizer, and water.
Dependencies are inferred from the claim text.