Medicament comprising combination of sepetaprost and Rho-associated coiled-coil containing protein kinase inhibitor
AssigneeSanten Pharmaceutical Co., Ltd.
InventorsYasuko Yamamoto, Takazumi Taniguchi
Life of this patent
Estimating the term…
Abstract
Described is a combination of a prophylactic or therapeutic agent for glaucoma or ocular hypertension, which is useful as a prophylactic or therapeutic agent for glaucoma or ocular hypertension. By combining sepetaprost and a Rho-associated coiled-coil containing protein kinase inhibitor(s), an intraocular pressure lowering action is enhanced as compared with the case where each drug is used alone. As the form of administration, they may be administered concomitantly or may be administered as a combination drug.
Claims14
A therapeutic agent for glaucoma or ocular hypertension, wherein sepetaprost and a Rho-associated coiled-coil containing protein kinase inhibitor(s) are administered in combination, and
- wherein the Rho-associated coiled-coil containing protein kinase inhibitor(s) is at least one selected from the group consisting of ripasudil and a salt thereof, and
- wherein sepetaprost and the Rho-associated coiled-coil containing protein kinase inhibitor(s) are administered simultaneously or concomitantly.
A therapeutic agent for glaucoma or ocular hypertension comprising sepetaprost, which is used concomitantly with a Rho-associated coiled-coil containing protein kinase inhibitor(s),
- wherein the Rho-associated coiled-coil containing protein kinase inhibitor(s) is at least one selected from the group consisting of ripasudil and a salt thereof.
A therapeutic method for glaucoma or ocular hypertension comprising:
- administering a therapeutically effective amount of sepetaprost and a therapeutically effective amount of a Rho-associated coiled-coil containing protein kinase inhibitor(s) to a subject in need thereof,
- wherein the Rho-associated coiled-coil containing protein kinase inhibitor(s) is at least one selected from the group consisting of ripasudil and a salt thereof, and
- wherein sepetaprost and the Rho-associated coiled-coil containing protein kinase inhibitor(s) are administered simultaneously or concomitantly.
Dependencies are inferred from the claim text.