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US 11,446,248 B2Granted
Process for the preparation of delayed release solid formulations
OwnerAntonio Enrico Seneciinventor
Life of this patent
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Abstract
A process for the preparation of oral delayed release solid formulations and the formulations obtainable from said process are now described. Said process comprises the following steps: a) melting at least one lipid; b) spraying said at least one melted lipid on at least one active ingredient in the form of a moving powder; c) cooling the resulting mixture; d) optional granulation of the mixture; e) optional compression of the mixture.
Claims18
Process for the preparation of a delayed release formulation for oral use comprising the following steps:
- a) melting at least one lipid to form a melted lipid, wherein said at least one lipid comprises a lipid comprising a fatty acid;
- b) spraying through a plurality of nozzles said at least one melted lipid on at least one active ingredient in the form of a moving powder, wherein said spaying is performed at a flow rate of 0.005-0.04 I/min per kg of active ingredient by nozzles arranged linearly with respect to a surface of the active ingredient advancement plane to form a resulting mixture;
- c) cooling the resulting mixture.
Dependencies are inferred from the claim text.