Stable topical compositions of fenoldopam
OwnerHelena Shifrin, Alexandra Shraifel +4inventors
InventorsHelena Shifrin, Alexandra Shraifel, Vered Rosenberger, Ron Schlinger, Tzviel Sheskin, Avi Avramoff
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Abstract
The present disclosure is directed to a topical composition, e.g., a physically and chemically stable topical composition of Fenoldopam comprising about 0.1% to about 5% by weight of Fenoldopam or a pharmaceutically acceptable salt thereof, at least one polyacrylamide-type gelling agent, at least one cellulose-type gelling agent, and at least one solvent, wherein the Fenoldopam is substantially solubilized in the composition, and wherein the composition is stable for at least twelve months at 25° C. and 60% relative humidity.
Claims20
A topical composition of Fenoldopam comprising about 0.1% to about 5% by weight of Fenoldopam or a pharmaceutically acceptable salt thereof, at least one polyacrylamide-type gelling agent, at least one cellulose-type gelling agent, and at least one solvent, wherein the Fenoldopam is substantially solubilized in the composition, and wherein the composition is physically and chemically stable for at least one month at 25° C. and 60% relative humidity.
Dependencies are inferred from the claim text.