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US 11,445,968 B2Granted
Quantitative heart testing
AssigneeHeart Test Laboratories, Inc.
InventorsGuangren Chen, David Krubsack, Mark Hilz
Life of this patent
Estimating the term…
Abstract
Heart condition and function can be quantified using repolarization measures and/or repolarization indices derived from a time-frequency transform of an electrocardiogram, e.g., based on points in time associated with the T wave. The electrocardiograms, time-frequency maps derived therefrom, and/or indices obtained by analysis of the time-frequency maps and electrocardiograms may be assembled into a user interface. Further embodiments are described.
Claims20
A method comprising:
- receiving one or more electrocardiograms acquired for a patient for one or more respective leads;
- converting the one or more electrocardiograms by time-frequency transform into one or more respective two-dimensional time-frequency maps;
- identifying, within the one or more electrocardiograms, one or more points in time associated with a T wave;
- determining, for at least one of the one or more time-frequency maps, one or more repolarization measures corresponding to extrema of the respective time-frequency map at the one or more points in time associated with the T wave;
- and
- outputting at least one repolarization index based on the one or more repolarization measures.
3 more elements
A heart test system comprising:
- one or more computer processors;
- and
- memory storing instructions for execution by the one or more computer processors, the instructions, when executed, causing the one or more computer processors to process one or more electrocardiograms acquired for a patient for one or more respective leads by performing operations comprising:
- converting the one or more electrocardiograms by time-frequency transform into one or more respective two-dimensional time-frequency maps;
- identifying, within the one or more electrocardiograms, one or more points in time associated with a T wave;
- determining, for at least one of the one or more time-frequency maps, one or more repolarization measures corresponding to extrema of the respective time-frequency map at the one or more points in time associated with the T wave;
- and
- causing display to a user, on a display device or in a printable report, of at least one repolarization index determined based on the one or more repolarization measures.
5 more elements
A heart test system comprising:
- one or more computer processors;
- and
- memory storing instructions for execution by the one or more computer processors, the instructions, when executed, causing the one or more computer processors to process one or more electrocardiograms acquired for a patient for one or more respective leads by performing operations comprising:
- converting the one or more electrocardiograms by time-frequency transform into one or more respective two-dimensional time-frequency maps;
- identifying, within the one or more electrocardiograms, points in time associated with a T wave, the points in time comprising at least a first point in time preceding the maximum of the T wave and a second point in time following the maximum of the T wave;
- determining, for at least one of the one or more time-frequency maps, repolarization measures corresponding to extrema of the respective time-frequency map at the one or more points in time associated with the T wave, the repolarization measure comprising a first repolarization measure corresponding to an extremum of the respective time-frequency map at the first point in time associated with the T wave and a second repolarization measure corresponding to an extremum of the respective time-frequency map at the second point in time associated with the T wave;
- and
- comparing the first repolarization measure with the second repolarization measure and determining a heart condition based on the comparison.
5 more elements
A heart test system comprising:
- one or more computer processors;
- and
- memory storing instructions for execution by the one or more computer processors, the instructions, when executed, causing the one or more computer processors to process electrocardiograms acquired for a patient for respective leads, including at least one electrocardiogram and respective lead associated with a left ventricle of the patient's heart and at least one electrocardiogram and respective lead associated with a right ventricle of the patient's heart, by performing operations comprising:
- converting the electrocardiograms by time-frequency transform into respective two-dimensional time-frequency maps;
- identifying, within electrocardiograms, one or more points in time associated with a T wave;
- determining one or more repolarization measures for the left ventricle from one or more time-frequency maps computed from the at least one electrocardiogram associated with the left ventricle, and determining one or more repolarization measures for the right ventricle from one or more time-frequency maps computed from the at least one electrocardiogram associated with the right ventricle, the repolarization measures corresponding to extrema of the respective time-frequency map at the one or more points in time associated with the T wave;
- comparing a left ventricular repolarization index determined based on the one or more repolarization measures determined for the left ventricle with a right ventricular repolarization index determined based on the one or more repolarization measures determined for the right ventricle;
- and
- determining an abnormal heart condition based on the right ventricular repolarization index being greater than the left ventricular repolarization index.
6 more elements
A heart test system comprising:
- one or more computer processors;
- and
- memory storing instructions for execution by the one or more computer processors, the instructions, when executed, causing the one or more computer processors to process one or more electrocardiograms acquired for a patient for one or more respective leads by performing operations comprising:
- converting the one or more electrocardiograms by time-frequency transform into one or more respective two-dimensional time-frequency maps;
- identifying, within the one or more electrocardiograms, one or more points in time associated with a T wave;
- determining, for at least one of the one or more time-frequency maps, one or more repolarization measures corresponding to extrema of the respective time-frequency map at the one or more points in time associated with the T wave;
- and
- determining a heart condition based on a comparison of at least one repolarization index determined based on the one or more repolarization measures against a threshold.
5 more elements
Dependencies are inferred from the claim text.